| Catalog No. | Size | Price (USD) |
| 13909-R402-B-20 | 20 µg | $118.49 |
| 13909-R402-B-100 | 100 µg | $370.28 |
General Information
| Product name | Recombinant Anti-Factor VIII Antibody (Biotin), Rabbit Monoclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human Factor VIII |
| Immunogen | Recombinant Human Coagulation Factor VIII / FVIII / F8 protein |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human Coagulation Factor VIII / FVIII / F8 protein and then biotinylated. |
| Source | Monoclonal Rabbit IgG Clone #402 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Biotin |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-AHF Antibody; Anti-DXS1253E Antibody; Anti-F8B Antibody; Anti-F8C Antibody; Anti-FVIII Antibody; Anti-HEMA Antibody; Anti-THPH13 Antibody
Background Information
| Full Name | coagulation factor VIII, procoagulant component |
| Description | Coagulation Factor VIII, also known as FVIII and F8, is a member of the multicopper oxidase family. Coagulation Factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. It contains 3 F5/8 type A domains, 2 F5/8 type C domains and 6 plastocyanin-like domains. FVIII is synthesized in the liver, and perhaps in other tissues. It is a coagulation cofactor which circulates bound to von Willebrand factor and is part of the intrinsic coagulation pathway. It is a macromolecular complex composed of two separate entities, one of which, when deficient, results in hemophilia A, and the other, when deficient, results in von Willebrand's disease. Hemophilia A is a disorder of blood coagulation characterized by a permanent tendency to hemorrhage. About 5% of patients have severe hemophilia resulting in frequent spontaneous bleeding into joints, muscles and internal organs. Less severe forms are characterized by bleeding after trauma or surgery. |
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