Produced in rabbits immunized with E. coli-derived Human AKAP10 fragment, and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
PBS, pH7.0 with 0.03% Proclin300
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.
The AKAP10 (also known as PRKA10; AKAP-10; D-AKAP2; D-AKAP-2) protein has a vital role in the maintenance of myometrial quiescence and pregnancy. The AKAP10 protein is ubiquitously expressed in thyroid, testis and other tissues. Structurally, the encoded AKAP10 protein is reported to be 73818 Da in mass. The AKAP10 gene encodes a member of the A-kinase anchor protein family. The encoded AKAP10 protein is localized to mitochondria and interacts with both the type I and type II regulatory subunits of PKA. Polymorphisms in AKAP10 gene may be associated with an increased risk of arrhythmias and sudden cardiac death.
References
Langmia IM, et al. (2015) Genetic association of akap10 gene polymorphism with reduced risk of preterm birth. J Perinatol 35 (9): 700-704.