Anti-FARSA Antibody, Rabbit Polyclonal sinobiological 203088-T46

$143.00
In stock
SKU
203088-T46
Catalog No.SizePrice (USD)
203088-T46-5050 µL$147.96
203088-T46-100100 µL$251.64
203088-T46-200200 µL$355.32

General Information

Product nameAnti-FARSA Antibody, Rabbit Polyclonal
Validated applicationsWB (FAQ Protocol), IHC-P (FAQ Protocol), ICC/IF (FAQ Protocol), IP (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman FARSA
ImmunogenE. coli-derived Human FARSA fragment
PreparationProduced in rabbits immunized with E. coli-derived Human FARSA fragment, and purified by antigen affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
FormulationPBS, pH7.0 with 0.03% Proclin300
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-CML33 Antibody; Anti-FARS Antibody; Anti-FARSL Antibody; Anti-FARSLA Antibody; Anti-FRSA Antibody; Anti-PheHA Antibody; Anti-RILDBC2 Antibody

Image / Experimental Information

Image 1 DescriptionAnti-FARSA rabbit polyclonal antibody at 1:500 dilution Lane A: U-251 MG Whole Cell Lysate Lane B: NIH-3T3 Whole Cell Lysate Lane C: 293T Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:58 kDa Observed band size:58 kDa
Image 1 Alt TextHuman FARSA Western blot (WB) 23782
Image 1 URLSource image
Image 2 DescriptionAnti-FARSA rabbit polyclonal antibody at 1:500 dilution Lane A: U-251 MG Whole Cell Lysate Lane B: NIH-3T3 Whole Cell Lysate Lane C: 293T Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:58 kDa Observed band size:58 kDa
Image 2 Alt TextHuman FARSA Immunohistochemistry(IHC) 23783
Image 2 URLSource image
Image 3 DescriptionAnti-FARSA rabbit polyclonal antibody at 1:500 dilution Lane A: U-251 MG Whole Cell Lysate Lane B: NIH-3T3 Whole Cell Lysate Lane C: 293T Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:58 kDa Observed band size:58 kDa
Image 3 Alt TextHuman FARSA Immunohistochemistry(IHC) 23784
Image 3 URLSource image
Image 4 DescriptionAnti-FARSA rabbit polyclonal antibody at 1:500 dilution Lane A: U-251 MG Whole Cell Lysate Lane B: NIH-3T3 Whole Cell Lysate Lane C: 293T Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:58 kDa Observed band size:58 kDa
Image 4 Alt TextHuman FARSA Immunofluorescence(IF) 23785
Image 4 URLSource image
Image 5 DescriptionAnti-FARSA rabbit polyclonal antibody at 1:500 dilution Lane A: U-251 MG Whole Cell Lysate Lane B: NIH-3T3 Whole Cell Lysate Lane C: 293T Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:58 kDa Observed band size:58 kDa
Image 5 Alt TextHuman FARSA Immunoprecipitation(IP) 23786
Image 5 URLSource image

Background Information

Full Namephenylalanyl-tRNA synthetase alpha subunit
DescriptionThe charging of tRNA molecules with phenylalanine in the cytoplasm is accomplished via a tetrameric enzyme that contains two catalytic subunits encoded by phenylalanyl-tRNA synthetase alpha (FARSA; MIM# 602918) and two regulatory subunits encoded by phenylalanyl-tRNA synthetase beta (FARSB; MIM# 609690). Aminoacyl-tRNA synthetases (ARSs) are ubiquitously expressed enzymes that ligate tRNA molecules to cognate amino acids, which is the first step of protein translation. Genetic mutations that cause dysfunction or absence of ARSs result in various neurodevelopmental disorders.
References
  1. Antonellis A, et al. (2018) Compound heterozygosity for loss-of-function farsb variants in a patient with classic features of recessive aminoacyl-trna synthetase-related disease. Hum Mutat 39 (6): 834-840.

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