Anti-Fas Ligand/TNFSF6 Antibody, Rabbit Polyclonal sinobiological 10244-T16

$143.00
In stock
SKU
10244-T16
Catalog No.SizePrice (USD)
10244-T16-5050 µL$147.96
10244-T16-100100 µL$251.64
10244-T16-200200 µL$355.32

General Information

Product nameAnti-Fas Ligand/TNFSF6 Antibody, Rabbit Polyclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman Fas Ligand/TNFSF6
ImmunogenRecombinant Human Fas Ligand/FASLG Protein (Catalog#10244-H07Y)
PreparationProduced in rabbits immunized with purified, recombinant Human Fas Ligand/FASLG (rh Fas Ligand/FASLG; Catalog#10244-H07Y; NP_000630.1; Pro134-Leu281). Fas Ligand/FASLG specific IgG was purified by Human Fas Ligand/FASLG affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
FormulationPBS, pH7.0 with 0.03% Proclin300
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-ALPS1B Antibody; Anti-APT1LG1 Antibody; Anti-APTL Antibody; Anti-CD178 Antibody; Anti-CD95-L Antibody; Anti-CD95L Antibody; Anti-FASL Antibody; Anti-TNFSF6 Antibody; Anti-TNLG1A Antibody

Background Information

Full NameFas ligand
DescriptionFas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.
Related Pathways
  • Death Receptor Signaling
  • p53 Pathway
References
  1. Pitti R M. et al., 1998, Nature. 396 (6712): 699-703.
  2. Hane M. et al., 1995, FEBS Lett. 373 (3): 265-8.
  3. Schneider P. et al., 1997, J Biol Chem. 272 (30): 18827-33.

Reviews

Write Your Own Review
You're reviewing:Anti-Fas Ligand/TNFSF6 Antibody, Rabbit Polyclonal sinobiological 10244-T16
Your Rating
Copyright © 2025 Biogege, Inc. All rights reserved.