Anti-FGF1 Antibody, Rabbit Polyclonal sinobiological 204233-T08

$143.00
In stock
SKU
204233-T08
Catalog No.SizePrice (USD)
204233-T08-5050 µL$147.96
204233-T08-100100 µL$251.64
204233-T08-200200 µL$355.32

General Information

Product nameAnti-FGF1 Antibody, Rabbit Polyclonal
Validated applicationsIHC-P (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman FGF1
ImmunogenE. coli-derived Human FGF1 fragment
PreparationProduced in rabbits immunized with E. coli-derived Human FGF1 fragment, and purified by antigen affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
FormulationPBS, pH7.0 with 0.03% Proclin300
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-AFGF Antibody; Anti-ECGF Antibody; Anti-ECGF-beta Antibody; Anti-ECGFA Antibody; Anti-ECGFB Antibody; Anti-FGF-1 Antibody; Anti-FGF-alpha Antibody; Anti-FGFA Antibody; Anti-GLIO703 Antibody; Anti-HBGF-1 Antibody; Anti-HBGF1 Antibody

Image / Experimental Information

Image 1 DescriptionImmunochemical staining of human FGF1 in human kidney with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
Image 1 Alt TextHuman FGF1 Immunohistochemistry(IHC) 33407
Image 1 URLSource image

Background Information

Full Namefibroblast growth factor 1 (acidic)
DescriptionaFGF, also known as FGF1 and HBGF-1, is a member of the fibroblast growth factor family. The biological activity of aFGF protein is exerted through binding to four high affinity cell surface receptors (FGFR1–4), which results in receptor dimerization and transphosphorylation in the tyrosine kinase domain. aFGF protein shows a wide range of endocrine-like activities. As a multiple function growth factor, this protein is involved in embryo development and tissue repair. Additionally, this protein is considered to function in several important physiological and pathological processes, such as embryonic development, morphogenesis, angiogenesis, wound healing and atheromatosis, carcinogenesis, development, and invasion of cancer.
Related Pathways
  • Actin Dynamics Signaling Pathway
  • G Protein-coupled Receptors Signaling
  • MAPK-Erk Pathway
  • Autophagy Pathway
References
  1. Jaye M., et al. ,(1986), Human endothelial cell growth factor: cloning, nucleotide sequence, and chromosome localization. Science 233:541-545.
  2. Mergia A., et al. , (1989), Structural analysis of the gene for human acidic fibroblast growth factor.Biochem. Biophys. Res. Commun. 164:1121-1129.
  3. Wang W.P., et al. ,(1989), Cloning of the gene coding for human class 1 heparin-binding growth factor and its expression in fetal tissues.Mol. Cell. Biol. 9:2387-2395.

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