| Catalog No. | Size | Price (USD) |
| 310358-T40-50 | 50 µL | $147.96 |
| 310358-T40-100 | 100 µL | $251.64 |
| 310358-T40-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-FHIT Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human FHIT |
| Immunogen | E. coli-derived Human FHIT fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human FHIT fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-AP3Aase Antibody; Anti-FRA3B Antibody
Image / Experimental Information
| Image 1 Description | Anti-FHIT rabbit polyclonal antibody at 1:500 dilution Lane A: HL-60 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:17 kDa |
| Image 1 Alt Text | Human FHIT Western blot (WB) 33961 |
| Image 1 URL | Source image |
| Image 2 Description | Anti-FHIT rabbit polyclonal antibody at 1:500 dilution Lane A: HL-60 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:17 kDa |
| Image 2 Alt Text | Human FHIT Immunohistochemistry(IHC) 33962 |
| Image 2 URL | Source image |
Background Information
| Full Name | fragile histidine triad |
| Description | Fragile histidine triad, also known as FHIT, may play a key role in differentiating humans from apes. Fragile histidine triad gene belongs to the histidine triad gene family. It has been shown that fragile histidine triad synergizes with VHL, another tumor suppressor, in protecting against chemically - induced lung cancer. Fragile histidine triad gene works as a tumor suppressor as it has been demonstrated in animal studies. The exact molecular function of FHIT is still partially unclear. It also acts as a tumor suppressor of HER2/neu driven breast cancer. |
| Research Areas |
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| References |
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