Produced in rabbits immunized with E. coli-derived Human FOXA1 fragment, and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
PBS, pH7.0 with 0.03% Proclin300
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.
Forkhead box protein A1 (FOXA1) was identified as a direct target of miR-132 in thyroid cancer cells. miR-132 acts as a tumor suppressor in thyroid cancer through targeting FOXA1. According to androgen receptor (AR) and forkhead box A1 (FOXA1) are determined and a lack of both biomarkers is an independent poor prognostic factor in ER-positive tumors. FOXA1 is a transcription factor capable to bind silenced chromatin to direct context-dependent cell fate conversion. FOXA1 can be used as potential targets for ESCC therapy.