| Catalog No. | Size | Price (USD) |
| 310224-T36-50 | 50 µL | $147.96 |
| 310224-T36-100 | 100 µL | $251.64 |
| 310224-T36-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-FOXP3 Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), IP (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human FOXP3 |
| Immunogen | E. coli-derived Human FOXP3 fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human FOXP3 fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-AIID Antibody; Anti-DIETER Antibody; Anti-IPEX Antibody; Anti-JM2 Antibody; Anti-PIDX Antibody; Anti-SCURFIN Antibody; Anti-XPID Antibody
Image / Experimental Information
| Image 1 Description | Anti-FOXP3 rabbit polyclonal antibody at 1:500 dilution Lane A: HeLa Whole Cell Lysate Lane B: Jurkat Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:47 kDa Observed band size:55 kDa |
| Image 1 Alt Text | Human FOXP3 Western blot (WB) 29132 |
| Image 1 URL | Source image |
| Image 2 Description | Anti-FOXP3 rabbit polyclonal antibody at 1:500 dilution Lane A: HeLa Whole Cell Lysate Lane B: Jurkat Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:47 kDa Observed band size:55 kDa |
| Image 2 Alt Text | Human FOXP3 Immunoprecipitation(IP) 29133 |
| Image 2 URL | Source image |
Background Information
| Full Name | forkhead box P3 |
| Description | Forkhead box P3 (FOXP3) is a key gene in the immune system which also plays a role in tumor development. The Treg cell lineage-specification factor FOXP3 (forkhead box P3) is essential for Treg cells' ability to uphold immunologic tolerance. Forkhead box protein 3 (FOXP3) is expressed in numerous types of tumor cell and is associated with tumor progression and prognosis. which had been reported that FOXP3 inhibited cellular proliferation and induced apoptosis of gastric cancer (GC) cells by activating the apoptosis signaling pathway. The elevated expression of FOXP3 in blood and urine samples from kidney transplant recipients could be a useful noninvasive biomarker to diagnose graft dysfunction. Forkhead box P3 (FOXP3), an X-linked tumor suppressor gene, plays an important role in breast cancer. |
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