Anti-GALE Antibody, Rabbit Polyclonal sinobiological 201426-T08

$143.00
In stock
SKU
201426-T08
Catalog No.SizePrice (USD)
201426-T08-5050 µL$147.96
201426-T08-100100 µL$251.64
201426-T08-200200 µL$355.32

General Information

Product nameAnti-GALE Antibody, Rabbit Polyclonal
Validated applicationsIHC-P (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman GALE
ImmunogenE. coli-derived Human GALE fragment
PreparationProduced in rabbits immunized with E. coli-derived Human GALE fragment, and purified by antigen affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-SDR1E1 Antibody; Anti-THC13 Antibody

Image / Experimental Information

Image 1 DescriptionImmunochemical staining of human GALE in human liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
Image 1 Alt TextHuman GALE Immunohistochemistry(IHC) 35155
Image 1 URLSource image
Image 2 DescriptionImmunochemical staining of human GALE in human liver with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.
Image 2 Alt TextHuman GALE Immunohistochemistry(IHC) 35156
Image 2 URLSource image

Background Information

Full NameUDP-galactose-4-epimerase
DescriptionUDP galactose-4'-epimerase, also known as GALE, enables the body to process a simple sugar called galactose, which is present in small amounts in many foods. Galactose is primarily part of a larger sugar called lactose, which is found in all dairy products and many baby formulas. UDP galactose-4'-epimerase catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. Defects in GALE causes epimerase-deficiency galactosemia (EDG), also known as galactosemia type 3. Clinical features include early-onset cataracts, liver damage, deafness and mental retardation.
References
  1. Kim W. et al., 2011, Mol Cell. 44 (2): 325-40.
  2. Lee KA. et al., 2011,. J Biol Chem. 286 (48): 41530-8.
  3. McCorvie TJ. et al., 2012, Biochim Biophys Acta. 1822 (10): 1516-26.

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