| Catalog No. | Size | Price (USD) |
| 10701-T16-50 | 50 µL | $147.96 |
| 10701-T16-100 | 100 µL | $251.64 |
General Information
| Product name | Anti-GM-CSF Receptor alpha Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human GM-CSF Receptor alpha |
| Immunogen | Recombinant Human GM-CSF Receptor alpha Protein (Catalog#10701-H08H) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human GM-CSF Receptor alpha (rh GM-CSF Receptor alpha; Catalog#10701-H08H; P15509-1; Met1-Gly320). GM-CSF Receptor alpha specific IgG was purified by Human GM-CSF Receptor alpha affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-alphaGMR Antibody; Anti-CD116 Antibody; Anti-CDw116 Antibody; Anti-CSF2R Antibody; Anti-CSF2RAX Antibody; Anti-CSF2RAY Antibody; Anti-CSF2RX Antibody; Anti-CSF2RY Antibody; Anti-GM-CSF-R-alpha Antibody; Anti-GMCSFR Antibody; Anti-GMCSFR-alpha Antibody; Anti-GMR Antibody; Anti-GMR-alpha Antibody; Anti-SMDP4 Antibody
Background Information
| Full Name | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| Description | CD116/GM-CSFR has been preferentially associated with M4, M5 subtype of AML but is not specific. The cluster of differentiation (cluster of designation) (often abbreviated as CD) is a protocol used for the identification and investigation of cell surface molecules present on white blood cells initially but found in almost any kind of cell of the body, providing targets for immunophenotyping of cells. Physiologically, CD molecules can act in numerous ways, often acting as receptors or ligands (the molecule that activates a receptor) important to the cell. A signal cascade is usually initiated, altering the behavior of the cell (see cell signaling). Some CD proteins do not play a role in cell signaling, but have other functions, such as cell adhesion. CD116/GM-CSFR is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. CD116/GM-CSFR is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. |
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