| Catalog No. | Size | Price (USD) |
| 105668-T08-50 | 50 µL | $147.96 |
| 105668-T08-100 | 100 µL | $251.64 |
| 105668-T08-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-ALDH3A2 Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human ALDH3A2 |
| Immunogen | A synthetic peptide corresponding to the C-terminus of the Human ALDH3A2 |
| Preparation | Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human ALDH3A2, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-ALDH10 Antibody; Anti-FALDH Antibody; Anti-SLS Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human ALDH3A2 in human liver with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human ALDH3A2 Immunohistochemistry(IHC) 20465 |
| Image 1 URL | Source image |
Background Information
| Full Name | aldehyde dehydrogenase 3 family, member A2 |
| Description | Sjögren-Larsson syndrome (SLS) is a rare type of congenital ichthyosis with neurological problems and intellectual disability. Homozygous mutations in ALDH3A2 gene are known to be responsible for this syndrome. An ALDH3A2 gene mutation results in dysfunction of the microsomal enzyme fatty aldehyde dehydrogenase and impaired metabolism and accumulation of leukotriene B4, which is a key molecule and a pro-inflammatory mediator in developing allergic diseases, especially asthma. An increased level of leukotriene B4 has been reported in SLS patients. |
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