Anti-HADH Antibody, Rabbit Polyclonal sinobiological 205688-T46

$143.00
In stock
SKU
205688-T46
Catalog No.SizePrice (USD)
205688-T46-5050 µL$147.96
205688-T46-100100 µL$251.64
205688-T46-200200 µL$355.32

General Information

Product nameAnti-HADH Antibody, Rabbit Polyclonal
Validated applicationsWB (FAQ Protocol), IHC-P (FAQ Protocol), ICC/IF (FAQ Protocol), IP (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman HADH
ImmunogenE. coli-derived Human HADH fragment
PreparationProduced in rabbits immunized with E. coli-derived Human HADH fragment, and purified by antigen affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
FormulationPBS, pH7.0 with 0.03% Proclin300
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-HAD Antibody; Anti-HAD1 Antibody; Anti-HADH1 Antibody; Anti-HADHSC Antibody; Anti-HCDH Antibody; Anti-HHF4 Antibody; Anti-MSCHAD Antibody; Anti-SCHAD Antibody

Image / Experimental Information

Image 1 DescriptionAnti-HADH rabbit polyclonal antibody at 1:500 dilution Lane A: 293T Whole Cell Lysate Lane B: A431 Whole Cell Lysate Lane C: HeLa Whole Cell Lysate Lane D: HepG2 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:34 kDa Observed band size:34 kDa
Image 1 Alt TextHuman HADH Western blot (WB) 31282
Image 1 URLSource image
Image 2 DescriptionAnti-HADH rabbit polyclonal antibody at 1:500 dilution Lane A: 293T Whole Cell Lysate Lane B: A431 Whole Cell Lysate Lane C: HeLa Whole Cell Lysate Lane D: HepG2 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:34 kDa Observed band size:34 kDa
Image 2 Alt TextHuman HADH Immunohistochemistry(IHC) 31283
Image 2 URLSource image
Image 3 DescriptionAnti-HADH rabbit polyclonal antibody at 1:500 dilution Lane A: 293T Whole Cell Lysate Lane B: A431 Whole Cell Lysate Lane C: HeLa Whole Cell Lysate Lane D: HepG2 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:34 kDa Observed band size:34 kDa
Image 3 Alt TextHuman HADH Immunohistochemistry(IHC) 31284
Image 3 URLSource image
Image 4 DescriptionAnti-HADH rabbit polyclonal antibody at 1:500 dilution Lane A: 293T Whole Cell Lysate Lane B: A431 Whole Cell Lysate Lane C: HeLa Whole Cell Lysate Lane D: HepG2 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:34 kDa Observed band size:34 kDa
Image 4 Alt TextHuman HADH Immunofluorescence(IF) 31285
Image 4 URLSource image
Image 5 DescriptionAnti-HADH rabbit polyclonal antibody at 1:500 dilution Lane A: 293T Whole Cell Lysate Lane B: A431 Whole Cell Lysate Lane C: HeLa Whole Cell Lysate Lane D: HepG2 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:34 kDa Observed band size:34 kDa
Image 5 Alt TextHuman HADH Immunoprecipitation(IP) 31286
Image 5 URLSource image

Background Information

Full Namehydroxyacyl-CoA dehydrogenase
DescriptionHADH (Hydroxyacyl-CoA Dehydrogenase, also known as HADHSC) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene is a member of the 3-hydroxyacyl-CoA dehydrogenase gene family. The encoded protein functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. HADH is a key enzyme in fatty acid oxidation. It is widely expressed in fat, kidney, and other tissues. The downregulation of HADH promotes gastric cancer progression via activation of the Akt signaling pathway. Recessive mutations in the hydroxyacyl-CoA dehydrogenase (HADH) gene encoding the enzyme 3-hydroxyacyl-CoA dehydrogenase are a rare cause of diazoxide-responsive hyperinsulinemic hypoglycemia (HH).

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