| Catalog No. | Size | Price (USD) |
| 11048-RP02-20 | 20 µL | $88.87 |
| 11048-RP02-50 | 50 µL | $147.96 |
| 11048-RP02-100 | 100 µL | $251.64 |
| 11048-RP02-200 | 200 µL | $355.32 |
General Information
| Product name | Influenza A H5N1 (Avian Flu) Hemagglutinin / HA Antibody, Rabbit PAb |
| Validated applications | WB (FAQ Protocol) |
| Application notes | IHC, FCM, IF, IP et al. applications haven't been validated. (Antibody's applications haven't been validated with corresponding virus positive samples. Optimal concentrations/dilutions should be determined by the end user.) |
| Specificity | H5N1 (A/Anhui/1/2005) HA |
| Immunogen | Recombinant H5N1 HA protein |
| Preparation | Produced in rabbits immunized with purified, recombinant Influenza A virus H5N1 (Avian Flu) Hemagglutinin extracellular domain. Total IgG was purified by Protein A affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Background Information
| Full Name | Hemagglutinin |
| Description | The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host endosomal membrane with the viral membrane. The influenza virus Hemagglutinin (HA) protein is translated in cells as a single protein, HA, or hemagglutinin precursor protein. For viral activation, hemagglutinin precursor protein (HA) must be cleaved by a trypsin-like serine endoprotease at a specific site, normally coded for by a single basic amino acid (usually arginine) between the HA1 and HA2 domains of the protein. After cleavage, the two disulfide-bonded protein domains produce the mature form of the protein subunits as a prerequisite for the conformational change necessary for fusion and hence viral infectivity. |
| References |
|
title: Digital microfluidic chip with photopatterned reactive sites for direct biomolecules immobilization and magnetic beads-free immunoassay
authors: Qiudi Xu; Ke Liu; ...; Tao Zhang
journal: Sensors and Actuators B: Chemical
date: 2025-02-01
doi: 10.1016/j.snb.2024.136893
cited_by_count: 0
techniques: Blocking Assay; Labeling; Recombinant
bioz_score: 95
title: RNF185 regulates proteostasis in Ebolavirus infection by crosstalk between the calnexin cycle, ERAD, and reticulophagy
authors: Jing Zhang; Bin Wang; ...; Yong-Hui Zheng
journal: Nature Communications
date: 2022-10-12
pmcid: 9554868
cited_by_count: 6
techniques: Nucleic Acid Electrophoresis; Western Blot
bioz_score: 95
title: Protein disulfide isomerases (PDIs) negatively regulate ebolavirus structural glycoprotein expression in the endoplasmic reticulum (ER) via the autophagy-lysosomal pathway.
authors: Bin Wang; Jing Zhang; ...; Yong-Hui Zheng
journal: Autophagy
date: 2022-10-03
pmid: 35130104
doi: 10.1080/15548627.2022.2031381
cited_by_count: 22
bioz_score: 95
