| Catalog No. | Size | Price (USD) |
| 11055-MM01-20 | 20 µL | $118.49 |
| 11055-MM01-50 | 50 µL | $222.17 |
| 11055-MM01-100 | 100 µL | $370.28 |
General Information
| Product name | Influenza A H1N1 (Swine Flu 2009) Hemagglutinin / HA Antibody, Mouse MAb |
| Validated applications | ELISA (FAQ Protocol) |
| Application notes | IHC, FCM, IF, IP et al. applications haven't been validated. (Antibody's applications haven't been validated with corresponding virus positive samples. Optimal concentrations/dilutions should be determined by the end user.) |
| Specificity | H1N1 (A/California/04/2009) HA H1N1 (A/California/07/2009) HA Has cross-reactivity in ELISA with H1N2 (A/swine/Guangxi/13/2006) HA No cross-reactivity in ELISA with H1N1 (A/Brisbane/59/2007) HA H1N1 (A/BrevigMission/1/1918) HA H1N1 (A/Solomon Islands/3/2006) HA H1N1 (A/Ohio/UR06-0091/2007) HA H1N1 (A/New Caledonia/20/1999) HA H1N1 (A/Puerto Rico/8/1934) HA H1N1 (A/WSN/1933) HA H1N3 (A/duck/NZL/160/1976) HA H3N2 (A/Brisbane/10/2007) HA H5N1 (A/Anhui/1/2005) HA H5N1 (A/Indonesia/5/2005) HA H5N1 (A/Viet nam/1194/2004) HA H5N1 (A/bar-headed goose/Qinghai/14/2008) HA H5N1 (A/turkey/Turkey/1/2005) HA Influenza B (B/Florida/4/2006) HA |
| Immunogen | Recombinant H1N1 HA protein |
| Preparation | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Influenza A virus H1N1 hemagglutinin (HA) extracellular domain. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Source | Monoclonal Mouse IgG1 Clone #6A4D1D1 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Background Information
| Full Name | Hemagglutinin |
| Description | The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host endosomal membrane with the viral membrane. The influenza virus Hemagglutinin (HA) protein is translated in cells as a single protein, HA, or hemagglutinin precursor protein. For viral activation, hemagglutinin precursor protein (HA) must be cleaved by a trypsin-like serine endoprotease at a specific site, normally coded for by a single basic amino acid (usually arginine) between the HA1 and HA2 domains of the protein. After cleavage, the two disulfide-bonded protein domains produce the mature form of the protein subunits as a prerequisite for the conformational change necessary for fusion and hence viral infectivity. |
| References |
|
title: Monitoring Vaccine-Induced Antibody Levels Using Carbon Nanotube-Based Field-Effect Transistors
authors: Amir Amiri; Wenting Shao; ...; Alexander Star
journal: Analytical Chemistry
date: 2025-11-03
pmid: 41182963
cited_by_count: 0
techniques: Recombinant
bioz_score: 95
title: Functionalized gold nanoflowers on carbon screen-printed electrodes: an electrochemical platform for biosensing hemagglutinin protein of influenza A H1N1 virus
authors: Carlos Enrique Torres-Méndez; Sharmilee Nandi; ...; Muhammad Anwaar Nazeer
journal: Beilstein Journal of Nanotechnology
date: 2025-01-01
pmcid: 12018907
cited_by_count: 0
techniques: Enzyme-linked Immunosorbent Assay
bioz_score: 95
title: Label-Free and Colorimetric Detection of Influenza A Virus via Receptor-Mediated Viral Fusion with Plasmonic Vesicles.
authors: Yesol Moon; Sojeong Lee; ...; Seungjoo Haam
journal: Small (Weinheim an Der Bergstrasse, Germany)
date: 2024-01-26
pmid: 37712175
doi: 10.1002/smll.202305748
cited_by_count: 1
techniques: Avidin-Biotin Assay; Molecular Weight; Pore Size; Saline
bioz_score: 95
title: Antigenic differences between AS03 adjuvanted influenza A (H1N1) pandemic vaccines: implications for pandemrix-associated narcolepsy risk.
authors: Outi Vaarala; Arja Vuorela; ...; Terhi Kilpi
journal: PLoS ONE
date: 2015-11-30
pmid: 25501681
doi: 10.1371/journal.pone.0114361
cited_by_count: 43
techniques: Binding Assay; Comparison; Derivative Assay; Dot Blot; Immunostaining; Isolation; Mass Spectrometry; Membrane; Molecular Weight; Suspension; Virus; Western Blot
bioz_score: 95
