| Catalog No. | Size | Price (USD) |
| 11055-RP07-1 | 1 mg | $1,377.43 |
| 11055-RP07-50 | 50 µg | $148.11 |
| 11055-RP07-100 | 100 µg | $266.60 |
General Information
| Product name | Influenza A H1N1 (Swine Flu 2009) Hemagglutinin / HA Antibody (HRP), Rabbit PAb, Antigen Affinity Purified |
| Validated applications | WB (FAQ Protocol), ELISA(Det) (FAQ Protocol) |
| Application notes | (Antibody's applications have not been validated with corresponding viruses. Optimal concentrations/dilutions should be determined by the end user.) |
| Specificity | H1N1 (A/California/04/2009) HA H1N1 (A/California/07/2009) HA |
| Immunogen | Recombinant H1N1 HA protein |
| Preparation | Produced in rabbits immunized with purified, recombinant Influenza A virus H1N1 (Swine Flu 2009) Hemagglutinin extracellular domain. H1N1 Hemagglutinin / HA specific IgG was purified by Influenza A virus H1N1 Hemagglutinin / HA affinity chromatography, and conjugated with horseradish peroxidase (HRP). |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS with 50 % HRP-protector, pH 7.4 |
| Conjugate | HRP |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! |
Background Information
| Full Name | Hemagglutinin |
| Description | The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host endosomal membrane with the viral membrane. The influenza virus Hemagglutinin (HA) protein is translated in cells as a single protein, HA, or hemagglutinin precursor protein. For viral activation, hemagglutinin precursor protein (HA) must be cleaved by a trypsin-like serine endoprotease at a specific site, normally coded for by a single basic amino acid (usually arginine) between the HA1 and HA2 domains of the protein. After cleavage, the two disulfide-bonded protein domains produce the mature form of the protein subunits as a prerequisite for the conformational change necessary for fusion and hence viral infectivity. |
| References |
|
title: Transient skin stretching stimulates immune surveillance and promotes vaccine delivery via hair follicles.
authors: Faiza Benaouda; Darawan Tabtim-On; ...; Elodie Segura
journal: Cell Reports
date: 2025-09-03
pmid: 40967214
doi: 10.1016/j.celrep.2025.116224
cited_by_count: 0
techniques: Recombinant; Staining
bioz_score: 95
title: Multiplexed Capillary-Flow Driven Immunoassay for Respiratory Illnesses.
authors: Jeremy S Link; John O'Donnell-Sloan; ...; Charles S Henry
journal: Analytical Chemistry
date: 2024-03-13
pmid: 38417100
doi: 10.1021/acs.analchem.3c04977
cited_by_count: 1
techniques: Adsorption; Blocking Assay; Membrane
bioz_score: 95
title: 3-O-Galloylated Procyanidins from Rumex acetosa L. Inhibit the Attachment of Influenza A Virus
authors: Andrea Derksen; Andreas Hensel; ...; Cheryl A. Stoddart
journal: PLoS ONE
date: 2014-10-10
pmid: 25303676
doi: 10.1371/journal.pone.0110089
pmcid: 4193892
cited_by_count: 34
techniques: Activity Assay; Cytotoxicity Assay; Incubation; Purification; Recombinant; Two Tailed Test; Western Blot
bioz_score: 95
