| Catalog No. | Size | Price (USD) |
| 11082-MM04-20 | 20 µL | $118.49 |
| 11082-MM04-50 | 50 µL | $222.17 |
| 11082-MM04-100 | 100 µL | $370.28 |
General Information
| Product name | Anti-H7N9 Hemagglutinin / HA Antibody, Mouse MAb |
| Validated applications | WB (FAQ Protocol), ELISA (FAQ Protocol) |
| Application notes | IHC, FCM, IF, IP et al. applications haven't been validated. (Antibody's applications haven't been validated with corresponding virus positive samples. Optimal concentrations/dilutions should be determined by the end user.) |
| Specificity | Anti-H7N9 HA / Hemagglutinin Has cross-reactivity in ELISA with H7N9 (A/Anhui/1/2013) HA Protein (Cat# 40103-V08B) H7N9 (A/Shanghai/1/2013) HA Protein (Cat# 40104-V08H) H7N9 (A/Hangzhou/1/2013) HA Protein (Cat# 40105-V08B) H7N9 (A/Pigeon/Shanghai/S1069/2013) HA Protein (Cat# 40106-V08H) H7N9 (A/Hangzhou/3/2013) HA Protein (Cat# 40123-V08B) H7N9 (A/Zhejiang/1/2013) HA Protein (Cat# 40125-V08B) H7N9 (A/Shanghai/4664T/2013) HA Protein (Cat# 40126-V08B) H7N9 (A/Shanghai/2/2013) HA Protein (Cat# 40239-V08H) H7N9 (A/Zhejiang/DTID-ZJU10/2013) HA Protein (Cat# 40325-V08B) H7N2 (A/ruddy turnstone/New Jersey/563/2006) HA Protein (Cat# 40170-V08B) H7N3 (A/turkey/Italy/214845/2002) HA Protein (Cat# 40128-V08B) H7N7 (A/chicken/Netherlands/1/03) HA Protein (Cat# 11212-V08B) H7N7 (A/equine/Kentucky/1a/1975) HA Protein (Cat# 40171-V08B) H7N7 (A/Netherlands/219/2003) HA Protein (Cat# 11082-V08B) H7N8 (A/mallard/Netherlands/33/2006) HA Protein (Cat# 40172-V08B) H3N2 (A/Brisbane/10/2007) HA Protein (Cat# 11056-V08H) H4N6 (A/mallard/Ohio/657/2002) HA Protein (Cat# 11714-V08H) H10N3 (A/duck/Hong Kong/786/1979) HA Protein (Cat# 11693-V08H) H13N8 (A/black-headed gull/Netherlands/1/00) HA Protein (Cat# 11721-V08H) No cross-reactivity in ELISA with H1N1 (A/Brisbane/59/2007) HA Protein (Cat# 11052-V08H) H2N2 (A/Canada/720/2005) HA Protein (Cat# 11688-V08H) H5N1 (A/Anhui/1/2005) HA Protein (Cat# 11048-V08H1) H6N1 (A/northern shoveler/California/HKWF115/2007) HA Protein (Cat# 11723-V08H) H7N1 (A/turkey/Italy/4602/99) HA1 Protein (Cat# 40169-V08H1) H7N7 (A/Netherlands/219/2003) HA1 Protein (Cat# 11082-V08H1) H8N4 (A/pintail duck/Alberta/114/1979) HA Protein (Cat# 11722-V08H) H9N2 (A/Hong Kong/1073/99) HA Protein (Cat# 11229-V08H) H11N2 (A/duck/Yangzhou/906/2002) HA Protein (Cat# 11705-V08H) H12N5 (A/green-winged teal/ALB/199/1991) HA Protein (Cat# 11718-V08H) H15N8 (A/duck/AUS/341/1983) HA Protein (Cat# 11720-V08H) H16N3 (A/black-headed gull/Sweden/5/99) HA Protein (Cat# 11711-V08H) Influenza B (B/Florida/4/2006) HA Protein (Cat# 11053-V08H) |
| Source | Monoclonal Mouse IgG2b Clone #04 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Background Information
| Full Name | Hemagglutinin |
| Description | The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host endosomal membrane with the viral membrane. The influenza virus Hemagglutinin (HA) protein is translated in cells as a single protein, HA, or hemagglutinin precursor protein. For viral activation, hemagglutinin precursor protein (HA) must be cleaved by a trypsin-like serine endoprotease at a specific site, normally coded for by a single basic amino acid (usually arginine) between the HA1 and HA2 domains of the protein. After cleavage, the two disulfide-bonded protein domains produce the mature form of the protein subunits as a prerequisite for the conformational change necessary for fusion and hence viral infectivity. |
| References |
|
title: Intranasal replicon vaccine establishes mucosal immunity and protects against H5N1 and H7N9 influenza
authors: Matthew R. Ykema; Michael A. Davis; ...; Emily A. Voigt
journal: Nature Communications
date: 2026-01-13
pmid: 41530119
doi: 10.1038/s41467-025-64829-6
cited_by_count: 0
techniques: Binding Assay; Blocking Assay; Control; Enzyme-linked Immunosorbent Assay; Neutralization; Plasmid Preparation; Transformation Assay
bioz_score: 95
title: Chimeric hemagglutinin and M2 mRNA vaccine for broad influenza subtype protection
authors: Dongrong Yi; Qian Liu; ...; Shan Cen
journal: NPJ vaccines
date: 2025-06-05
pmid: 40473642
cited_by_count: 2
techniques: Construct; Control; Enzyme-linked Immunosorbent Assay; Expressing; HAI Assay; Incubation; Injection; Neutralization; Recombinant; Staining; Two Tailed Test
bioz_score: 95
title: An intranasal, NLC-delivered self-amplifying RNA vaccine establishes protective immunity against pre-pandemic H5N1 and H7N9 influenza
authors: Ykema Matthew R.; Davis Michael A.; ...; Voigt Emily A.
journal: bioRxiv
date: 2025-01-10
doi: 10.1101/2025.01.07.631792
cited_by_count: 0
techniques: Binding Assay; Blocking Assay; Comparison; Control; Enzyme-linked Immunosorbent Assay; Neutralization; Plasmid Preparation; Positive Control; Transformation Assay; Virus
bioz_score: 95
title: Sphingomyelin-Sequestered Cholesterol Domain Recruits Formin-Binding Protein 17 for Constricting Clathrin-Coated Pits in Influenza Virus Entry.
authors: Bo Tang; En-Ze Sun; ...; Dai-Wen Pang
journal: Journal of virology
date: 2022-04-28
pmid: 35020471
doi: 10.1128/JVI.01813-21
cited_by_count: 7
techniques: Cell Culture; Column Chromatography; Fluorescence; Imaging; Incubation; Inverted Microscopy; Lysis; Microscopy; Purification; Recombinant; Sonication
bioz_score: 95
title: Characterization of Immune Response towards Generation of Universal Anti-HA-Stalk Antibodies after Immunization of Broiler Hens with Triple H5N1/NA-HA-M1 VLPs
authors: Beata Gromadzka; Milena Chraniuk; ...; Magdalena Materniak-Kornas
journal: Viruses
date: 2022-03-30
pmid: 35458460
doi: 10.3390/v14040730
pmcid: 9029564
cited_by_count: 2
techniques: Activity Assay; Comparison; Construct; Control; Electron Microscopy; Enzyme-linked Immunosorbent Assay; Expressing; HI Assay; Hemagglutination Assay; Infection; Negative Control; Peptide ELISA; Positive Control; Purification; Sequencing; Synthesized; Titration; Transfection; Transmission Assay; Virus; Western Blot
bioz_score: 95
title: Immune Evaluation of Recombinant Lactobacillus plantarum With Surface Display of HA1-DCpep in Mice
authors: Hui Niu; Jun-Hong Xing; ...; Chun-Feng Wang
journal: Frontiers in Immunology
date: 2021-12-01
pmid: 34925386
doi: 10.3389/fimmu.2021.800965
pmcid: 8673267
cited_by_count: 9
techniques: Flow Cytometry; Immunofluorescence; Incubation; Marker; Plasmid Preparation; Recombinant; Sonication; Western Blot
bioz_score: 95
title: Single Dose of Bivalent H5 and H7 Influenza Virus-Like Particle Protects Chickens Against Highly Pathogenic H5N1 and H7N9 Avian Influenza Viruses
authors: Jiao Hu; Peipei Peng; ...; Xiufan Liu
journal: Frontiers in Veterinary Science
date: 2021-11-11
pmid: 34859093
doi: 10.3389/fvets.2021.774630
pmcid: 8632145
cited_by_count: 12
techniques: Expressing; Fluorescence; HI Assay; Immunofluorescence; Immunopeptidomics; Incubation; Infection; Microscopy; Staining; Titration; Virus
bioz_score: 95
title: Identifying novel amino acid substitutions of hemagglutinin involved in virulence enhancement in H7N9 virus strains
authors: Ting Zhang; Haiwei Du; ...; Fan Yang
journal: Virology journal
date: 2021-01-11
pmid: 33430903
doi: 10.1186/s12985-020-01464-1
pmcid: 7798331
cited_by_count: 2
techniques: Activity Assay; Incubation; Infection; Labeling; Luciferase; Mutagenesis; Recombinant; Software; Western Blot
bioz_score: 95
title: Ultrasensitive Virion Immunoassay Platform with Dual-Modality Based on a Multifunctional Aggregation-Induced Emission Luminogen.
authors: Ling-Hong Xiong; Xuewen He; ...; Ben Zhong Tang
journal: ACS Nano
date: 2019-10-09
pmid: 30148962
doi: 10.1021/acsnano.8b05270
cited_by_count: 17
techniques: Plasmid Preparation; Purification
bioz_score: 95
title: Influenza nucleic acid molecules and vaccines made therefrom
authors: David B. Weiner; Jian Yan
date: 2019-09-03
cited_by_count: 0
techniques: Diagnostic Assay; Expressing; Incubation; Membrane; Microscopy; Plasmid Preparation; Software; Transfection
bioz_score: 95
title: TMPRSS2 Is the Major Activating Protease of Influenza A Virus in Primary Human Airway Cells and Influenza B Virus in Human Type II Pneumocytes
authors: Hannah Limburg; Anne Harbig; ...; Eva Böttcher-Friebertshäuser
journal: Journal of virology
date: 2019-08-07
pmid: 31391268
doi: 10.1128/JVI.00649-19
pmcid: 6803253
cited_by_count: 106
techniques: Activation Assay; Amplification; Control; Expressing; Immunofluorescence; Incubation; Infection; Isolation; Knockdown; Negative Control; Plaque Assay; Reverse Transcription Polymerase Chain Reaction; SDS Page; Sequencing; Staining; Virus; Western Blot
bioz_score: 95
title: Nanodiamond enhances immune responses in mice against recombinant HA/H7N9 protein
authors: Ngoc Bich Pham; Thuong Thi Ho; ...; Ha Hoang Chu
journal: Journal of Nanobiotechnology
date: 2017-10-05
pmid: 28982373
doi: 10.1186/s12951-017-0305-2
pmcid: 5629800
cited_by_count: 33
techniques: Affinity Chromatography; Blocking Assay; Construct; Enzyme-linked Immunosorbent Assay; Expressing; Incubation; Negative Control; Positive Control; Purification; Recombinant; Western Blot
bioz_score: 95
title: Preclinical and Clinical Demonstration of Immunogenicity by mRNA Vaccines against H10N8 and H7N9 Influenza Viruses
authors: Kapil Bahl; Joe J. Senn; ...; Giuseppe Ciaramella
journal: Molecular Therapy
date: 2017-06-07
pmid: 28457665
doi: 10.1016/j.ymthe.2017.03.035
pmcid: 5475249
cited_by_count: 481
techniques: Cell Culture; Enzyme-linked Immunosorbent Assay; Expressing; In Vitro; Incubation; Injection; Recombinant; Transfection
bioz_score: 95
title: Protective effects of phillyrin against influenza A virus in vivo.
authors: Xin-Yan Qu; Qing-Jun Li; ...; Sheng-Qi Wang
journal: Archives of pharmacal research
date: 2017-01-27
pmid: 27323762
doi: 10.1007/s12272-016-0775-z
cited_by_count: 46
techniques: Incubation; Western Blot
bioz_score: 95
title: Protective Immunity to H7N9 Influenza viruses elicited by synthetic DNA Vaccine
authors: Jian Yan; Daniel O. Villarreal; ...; David B. Weiner
journal: Vaccine
date: 2015-05-19
pmid: 24631084
doi: 10.1016/j.vaccine.2014.02.038
pmcid: 4221260
cited_by_count: 34
techniques: Diagnostic Assay; Incubation; Microscopy; Plasmid Preparation; Software; Transfection
bioz_score: 95
