| Catalog No. | Size | Price (USD) |
| 11699-RP01-20 | 20 µL | $88.87 |
| 11699-RP01-100 | 100 µL | $251.64 |
| 11699-RP01-200 | 200 µL | $370.28 |
General Information
| Product name | Influenza A H5N2 Hemagglutinin / HA Antibody, Rabbit PAb |
| Validated applications | WB (FAQ Protocol), ELISA (FAQ Protocol) |
| Application notes | IHC, FCM, IF, IP et al. applications haven't been validated. (Antibody's applications haven't been validated with corresponding virus positive samples. Optimal concentrations/dilutions should be determined by the end user.) |
| Specificity | H5N2 (A/American green-winge teal/California/HKWF609/07) HA / Hemagglutinin |
| Immunogen | Recombinant H5N2 (A/American green-winge teal/California/HKWF609/07) HA / Hemagglutinin protein (Catalog#11699-V08H) |
| Preparation | Produced in rabbits immunized with purified, recombinant H5N2 (A/American green-winge teal/California/HKWF609/07) HA / Hemagglutinin (Catalog#11699-V08H; ACF47563.1; Met 1-Gln 527). Total IgG was purified by Protein A affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Background Information
| Full Name | Hemagglutinin |
| Description | The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host endosomal membrane with the viral membrane. The influenza virus Hemagglutinin (HA) protein is translated in cells as a single protein, HA, or hemagglutinin precursor protein. For viral activation, hemagglutinin precursor protein (HA) must be cleaved by a trypsin-like serine endoprotease at a specific site, normally coded for by a single basic amino acid (usually arginine) between the HA1 and HA2 domains of the protein. After cleavage, the two disulfide-bonded protein domains produce the mature form of the protein subunits as a prerequisite for the conformational change necessary for fusion and hence viral infectivity. |
| References |
|
title: Optoelectronic fowl adenovirus detection based on local electric field enhancement on graphene quantum dots and gold nanobundle hybrid.
authors: Syed Rahin Ahmed; Jack Mogus; ...; Suresh Neethirajan
journal: Biosensors & bioelectronics
date: 2018-08-02
pmid: 29278812
doi: 10.1016/j.bios.2017.12.028
cited_by_count: 46
techniques: Blocking Assay; Recombinant
bioz_score: 95
title: Chiral MoS 2 Quantum Dots: Dual‐Mode Detection Approaches for Avian Influenza Viruses
authors: Syed Rahin Ahmed; Suresh Neethirajan
journal: Global Challenges
date: 2018-03-12
pmid: 31565328
doi: 10.1002/gch2.201700071
pmcid: 6607333
cited_by_count: 20
techniques: Blocking Assay; Recombinant
bioz_score: 95
title: Self-assembled Star-shaped Chiroplasmonic Gold Nanoparticles for Ultrasensitive Chiro-immunosensor of Viruses
authors: Ahmed Syed Rahin; Nagy Éva; Neethirajan Suresh
journal: bioRxiv
date: 2017-07-12
doi: 10.1101/162412
cited_by_count: 0
techniques: Blocking Assay; Recombinant
bioz_score: 95
title: Amplified visual immunosensor integrated with nanozyme for ultrasensitive detection of avian influenza virus
authors: Syed Rahin Ahmed; Juan C. Corredor; ...; Suresh Neethirajan
journal: Nanotheranostics
date: 2017-01-01
pmid: 29071197
doi: 10.7150/ntno.20758
pmcid: 5646732
cited_by_count: 27
techniques: Blocking Assay; Recombinant; Virus
bioz_score: 95
