| Catalog No. | Size | Price (USD) |
| 40103-T62-20 | 20 µL | $118.49 |
| 40103-T62-50 | 50 µL | $222.17 |
| 40103-T62-100 | 100 µL | $370.28 |
General Information
| Product name | Anti-H7N9 Hemagglutinin / HA Antibody, Rabbit PAb, Antigen Affinity Purified |
| Validated applications | WB (FAQ Protocol), ELISA (FAQ Protocol) |
| Application notes | IHC, FCM, IF, IP et al. applications haven't been validated. (Antibody's applications haven't been validated with corresponding virus positive samples. Optimal concentrations/dilutions should be determined by the end user.) |
| Specificity | H7N9 (A/Anhui/1/2013) HA |
| Immunogen | Recombinant Influenza A H7N9 (A/Anhui/1/2013) HA protein (Catalog#40103-V08B) |
| Preparation | Produced in rabbits immunized with purified, recombinant Influenza A H7N9 (A/Anhui/1/2013) HA (Catalog#40103-V08B; EPI439507; Met1-Val524). HA specific IgG was purified by Influenza A H7N9 (A/Anhui/1/2013) HA affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Image / Experimental Information
| Image 1 Description | Anti-Influenza A H7N9 (A/Anhui/1/2013) Hemagglutinin / HA rabbit polyclonal antibody at 1:50000 dilution. Sample：Influenza A H7N9 (A/Anhui/1/2013) Hemagglutinin / HA Recombinant Protein Lane A: 2ng Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. |
| Image 1 Alt Text | H7N9 Hemagglutinin/HA Western blot (WB) 30724 |
| Image 1 URL | Source image |
Background Information
| Full Name | Hemagglutinin |
| Description | The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host endosomal membrane with the viral membrane. The influenza virus Hemagglutinin (HA) protein is translated in cells as a single protein, HA, or hemagglutinin precursor protein. For viral activation, hemagglutinin precursor protein (HA) must be cleaved by a trypsin-like serine endoprotease at a specific site, normally coded for by a single basic amino acid (usually arginine) between the HA1 and HA2 domains of the protein. After cleavage, the two disulfide-bonded protein domains produce the mature form of the protein subunits as a prerequisite for the conformational change necessary for fusion and hence viral infectivity. |
| References |
|
title: Enhancing the breadth of protection in mice with a multivalent influenza vaccine
authors: Xiang Wang; Yixin Niu; ...; Dongming Zhou
journal: Communications Biology
date: 2026-01-07
pmid: 41501378
cited_by_count: 0
techniques: Virus
bioz_score: 95
title: Glucosidase alpha neutral C promotes influenza virus replication by inhibiting proteosome-dependent degradation of hemagglutinin
authors: Xinzhong Liao; Qian Xie; ...; Yuelong Shu
journal: Signal transduction and targeted therapy
date: 2025-04-23
pmid: 40263249
doi: 10.1038/s41392-025-02227-6
pmcid: 12015365
cited_by_count: 2
bioz_score: 95
title: A decavalent composite mRNA vaccine against both influenza and COVID-19
authors: Yang Wang; Qinhai Ma; ...; John A. Lednicky
journal: mBio
date: 2024-09-01
pmid: 39105586
pmcid: 11389412
cited_by_count: 9
techniques: Cell Culture; Control; Expressing; Formulation; Lysis; Transfection; Virus; Western Blot; Zeta Potential Analyzer
bioz_score: 95
title: A 10-valent composite mRNA vaccine against both influenza and COVID-19
authors: Wang Yang; Ma Qinhai; ...; Yang Zifeng
journal: bioRxiv
date: 2024-03-05
doi: 10.1101/2024.03.05.583547
cited_by_count: 0
techniques: Cell Culture; Expressing; Formulation; Lysis; Transfection; Virus; Western Blot
bioz_score: 95
title: Transcriptome profiling and protease inhibition experiments identify proteases that activate H3N2 influenza A and influenza B viruses in murine airways
authors: Anne Harbig; Marco Mernberger; ...; Eva Böttcher-Friebertshäuser
journal: The Journal of Biological Chemistry
date: 2020-08-14
pmid: 32303635
doi: 10.1074/jbc.RA120.012635
pmcid: 7450141
cited_by_count: 30
techniques: FLAG-tag; Protease Inhibitor; Recombinant
bioz_score: 95
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