Produced in rabbits immunized with E. coli-derived Human ALS2CR12 fragment, and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
PBS, pH7.0 with 0.03% Proclin300
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.
Image / Experimental Information
Image 1 Description
Anti-ALS2CR12 rabbit polyclonal antibody at 1:500 dilution Lane A: MCF7 Whole Cell Lysate Lane B: A549 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:52 kDa Observed band size:52 kDa
Anti-ALS2CR12 rabbit polyclonal antibody at 1:500 dilution Lane A: MCF7 Whole Cell Lysate Lane B: A549 Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:52 kDa Observed band size:52 kDa
ALS2CR12 (amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12), also known as FLACC1, is located on chromosome 2q33.1. The ALS2CR12 protein is associated with the fibrous sheath in the sperm flagellum.
References
Stacey SN, et al. (2015) New basal cell carcinoma susceptibility loci. Nat Commun 6 6825.
Lin WY, et al. (2015) Identification and characterization of novel associations in the casp8/als2cr12 region on chromosome 2 with breast cancer risk. Hum Mol Genet 24 (1): 285-298.
Choi E, et al. (2011) Expression of a sperm flagellum component encoded by the als2cr12 gene. Gene Expr Patterns 11 (5-6): 327-333.
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