| Catalog No. | Size | Price (USD) |
| 40324-T62-20 | 20 µL | $118.49 |
| 40324-T62-50 | 50 µL | $222.17 |
| 40324-T62-100 | 100 µL | $370.28 |
General Information
| Product name | Influenza H18N11 (A/flat-faced bat/Peru/033/2010) Hemagglutinin / HA1 Antibody, Rabbit PAb, Antigen Affinity Purified |
| Validated applications | WB (FAQ Protocol), ELISA (FAQ Protocol) |
| Application notes | IHC, FCM, IF, IP et al. applications haven't been validated. (Antibody's applications haven't been validated with corresponding virus positive samples. Optimal concentrations/dilutions should be determined by the end user.) |
| Specificity | Influenza H18N11 (A/flat-faced bat/Peru/033/2010) Hemagglutinin / HA1 |
| Immunogen | Recombinant Influenza H18N11 (A/flat-faced bat/Peru/033/2010) Hemagglutinin / HA1 Protein (Catalog#40324-V08H1) |
| Preparation | Produced in rabbits immunized with purified, recombinant Influenza H18N11 (A/flat-faced bat/Peru/033/2010) Hemagglutinin / HA1 (Catalog#40324-V08H1; AGX84934.1; Met1-Arg339). Influenza H18N11 (A/flat-faced bat/Peru/033/2010) Hemagglutinin / HA1 specific IgG was purified by Influenza H18N11 (A/flat-faced bat/Peru/033/2010) Hemagglutinin / HA1 affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Image / Experimental Information
| Image 1 Description | Anti-Influenza A H18N11 (A/flat-faced bat/Peru/033/2010) Hemagglutinin / HA1 rabbit polyclonal antibody at 1:1000 dilution. Sample:Influenza A H18N11 (A/flat-faced bat/Peru/033/2010) Hemagglutinin / HA1 Recombinant Protein Lane A: 50ng Lane B: 10ng Secondary Goat Anti- Rabbit IgG H&L (Dylight 800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. |
| Image 1 Alt Text | H18N11 HA Western blot (WB) 14101 |
| Image 1 URL | Source image |
Background Information
| Full Name | Hemagglutinin |
| Description | The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host endosomal membrane with the viral membrane. The influenza virus Hemagglutinin (HA) protein is translated in cells as a single protein, HA, or hemagglutinin precursor protein. For viral activation, hemagglutinin precursor protein (HA) must be cleaved by a trypsin-like serine endoprotease at a specific site, normally coded for by a single basic amino acid (usually arginine) between the HA1 and HA2 domains of the protein. After cleavage, the two disulfide-bonded protein domains produce the mature form of the protein subunits as a prerequisite for the conformational change necessary for fusion and hence viral infectivity. |
| References |
|
title: Dynamics of influenza transmission in vampire bats revealed by longitudinal monitoring and a large-scale anthropogenic perturbation.
authors: Megan E Griffiths; Alice Broos; ...; Mafalda Viana
journal: Science Advances
date: 2025-02-05
pmid: 39908385
cited_by_count: 0
techniques: Affinity Purification; Concentration Assay; Control; Enzyme-linked Immunosorbent Assay; Generated; Modification; Negative Control; Recombinant; Saline
bioz_score: 94
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