| Catalog No. | Size | Price (USD) |
| 86001-RM01-H-20 | 20 µg | $148.11 |
| 86001-RM01-H-100 | 100 µg | $518.39 |
General Information
| Product name | Influenza A Virus Hemagglutinin / HA Antibody (HRP), Rabbit MAb |
| Validated applications | ELISA (FAQ Protocol) |
| Specificity | H1N1 (A/California/04/2009) HA H1N1 (A/California/07/2009) HA |
| Immunogen | Recombinant H1N1 HA protein |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Influenza A virus H1N1 Hemagglutinin extracellular domain and conjugated with horseradish-peroxidase (HRP). |
| Source | Monoclonal Rabbit IgG Clone #2 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | HRP |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Protected from prolonged exposure to light. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Background Information
| Full Name | Hemagglutinin |
| Description | The influenza viral Hemagglutinin (HA) protein is a homotrimer with a receptor binding pocket on the globular head of each monomer.HA has at least 18 different antigens. These subtypes are named H1 through H18.HA has two functions. Firstly, it allows the recognition of target vertebrate cells, accomplished through the binding to these cells' sialic acid-containing receptors. Secondly, once bound it facilitates the entry of the viral genome into the target cells by causing the fusion of the host endosomal membrane with the viral membrane. The influenza virus Hemagglutinin (HA) protein is translated in cells as a single protein, HA, or hemagglutinin precursor protein. For viral activation, hemagglutinin precursor protein (HA) must be cleaved by a trypsin-like serine endoprotease at a specific site, normally coded for by a single basic amino acid (usually arginine) between the HA1 and HA2 domains of the protein. After cleavage, the two disulfide-bonded protein domains produce the mature form of the protein subunits as a prerequisite for the conformational change necessary for fusion and hence viral infectivity. |
| References |
|
title: Affinity Peptide-Tethered Suspension Hydrogel Sensor for Selective and Sensitive Detection of Influenza Virus.
authors: Ji Hong Kim; Hye-Seon Jeong; ...; Jong Pil Park
journal: ACS Applied Materials & Interfaces
date: 2023-10-30
pmid: 37903089
doi: 10.1021/acsami.3c14470
cited_by_count: 1
techniques: Fluorescence; Labeling; Saline; Sequencing; Virus
bioz_score: 91
