| Catalog No. | Size | Price (USD) |
| 17500-MM14-50 | 50 µL | $147.96 |
| 17500-MM14-100 | 100 µL | $251.64 |
| 17500-MM14-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-MIS/AMH Antibody, Mouse Monoclonal |
| Validated applications | IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human MIS/AMH |
| Immunogen | Recombinant Human AMH Protein (Catalog#17500-H07H) |
| Preparation | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human AMH (rh AMH; Catalog#17500-H07H; NP_000470.2; Leu25-Arg560). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Source | Monoclonal Mouse IgG1 Clone #14 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-MIF Antibody; Anti-MIS Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human AMH in human testis with mouse monoclonal antibody at 1:30 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human AMH Immunohistochemistry(IHC) 27415 |
| Image 1 URL | Source image |
Background Information
| Full Name | anti-Mullerian hormone |
| Description | Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and the FSH-dependent development of follicles. BMP15 up-regulates the transcription of AMH and that the inhibition of p38 MAPK decreases the BMP15-induced expression of AMH and SOX9, suggesting that BMP15 up-regulates the expression of AMH via the p38 MAPK signaling pathway, and this process involves the SOX9 transcription factor. AMH is widely used for assessing ovarian reserve, and it is particularly convenient, because it is thought to have minimal variability throughout the menstrual cycle. Fetal anti-Mullerian hormone (AMH) is responsible for normal male sexual differentiation, and circulating AMH is used as a marker of testicular tissue in newborns with disorders of sex development. Anti-Mullerian hormone (AMH) produced in the developing testis induces the regression of the Mullerian duct, which develops into the oviducts, uterus and upper vagina. As well as other hormone receptors, and a decreased ovarian cortex cell proliferation. These results help understand the inhibitory effects of AMH on follicular development. |
