Anti-HES7 Antibody, Rabbit Polyclonal sinobiological 201951-T10
$243.00
In stock
SKU
201951-T10
| Catalog No. | Size | Price (USD) |
| 201951-T10-100 | 100 µL | $251.64 |
General Information
| Product name | Anti-HES7 Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol), ICC/IF (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human HES7 |
| Immunogen | E. coli-derived Human HES7 fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human HES7 fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-bHLHb37 Antibody; Anti-hHes7 Antibody; Anti-SCDO4 Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human HES7 in human brain with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human HES7 Immunohistochemistry(IHC) 36224 |
| Image 1 URL | Source image |
| Image 2 Description | Immunochemical staining of human HES7 in human brain with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections. |
| Image 2 Alt Text | Human HES7 Immunofluorescence(IF) 36225 |
| Image 2 URL | Source image |
Background Information
| Description | Hes7 is a basic helix-loop-helix (bHLH) gene. In mouse, Hes7 has a conserved bHLH domain in the amino-terminal region and the WRPW domain at the carboxy-terminal end, like Hes1. The mouse Hes7 gene is located next to Aloxe3, which is mapped to a position 37.0 cM from the centromere on chromosome 11. Loss of Hes7 function leads to irregular somite formation demonstrating that Hes7 is a crucial component of the segmentation clock during somitogenesis. Hes7 is expressed in an oscillatory manner and regulates the periodic somite formation. Oscillatory expression of Hes7 depends on negative feedback and rapid degradation of the gene products. |
| References |
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