Produced in rabbits immunized with E. coli-derived Human HRASLS2 fragment, and purified by antigen affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
PBS, pH7.0 with 0.03% Proclin300
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.
Image / Experimental Information
Image 1 Description
Immunochemical staining of human HRASLS2 in human kidney with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.
The HRAS-like suppressor 2 (HRASLS2) gene belongs to the H-REV107 gene family involved in the regulation of cell growth and differentiation. HRASLS2 is expressed at high levels in normal tissues of the small intestine, kidney, and trachea. HRASLS2 functions in phospholipid metabolism as both a phospholipase and an N- and O-acyltransferase. HRASLS2 exhibits both phospholipase A1/2 and acyltransferase activities. HRASLS2 shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids.
References
Shyu RY, et al. (2008) Cloning and functional characterization of the hrasls2 gene. Amino Acids 35 (1): 129-137.
-HD13MA0885-500-human-kidney-IHC-P.png){kind=link}