| Catalog No. | Size | Price (USD) |
| 10066-R124-50 | 50 µL | $177.58 |
| 10066-R124-100 | 100 µL | $340.51 |
General Information
| Product name | Recombinant Anti-ALK-1 Antibody, Rabbit Monoclonal |
| Validated applications | WB (FAQ Protocol), IP (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human ALK-1 |
| Immunogen | Recombinant Human ALK-1 / ACVRL1 protein (Catalog#10066-H08H) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human ALK-1 / ACVRL1 (rh ALK-1 / ACVRL1; Catalog#10066-H08H; NP_000011.2; Met1-Gln118). |
| Source | Monoclonal Rabbit IgG Clone #124 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-ACVRLK1 Antibody; Anti-ALK-1 Antibody; Anti-ALK1 Antibody; Anti-HHT Antibody; Anti-HHT2 Antibody; Anti-ORW2 Antibody; Anti-SKR3 Antibody; Anti-TSR-I Antibody
Image / Experimental Information
| Image 1 Description | ALK1 was immunoprecipitated using: Lane A:0.5 mg MCF-7 Whole Cell Lysate Lane B:0.5 mg K562 Whole Cell Lysate 2 µL anti-ALK1 rabbit monoclonal antibody and 15 μl of 50 % Protein G agarose. Primary antibody: Anti-ALK1 rabbit monoclonal antibody,at 1:100 dilution Secondary antibody: Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution Developed using the odssey technique. Performed under reducing conditions. Predicted band size: 56 kDa Observed band size: 56 kDa |
| Image 1 Alt Text | Human ALK-1/ACVRL1 Immunoprecipitation(IP) 6123 |
| Image 1 URL | Source image |
| Image 2 Description | ALK1 was immunoprecipitated using: Lane A:0.5 mg MCF-7 Whole Cell Lysate Lane B:0.5 mg K562 Whole Cell Lysate 2 µL anti-ALK1 rabbit monoclonal antibody and 15 μl of 50 % Protein G agarose. Primary antibody: Anti-ALK1 rabbit monoclonal antibody,at 1:100 dilution Secondary antibody: Dylight 800-labeled antibody to rabbit IgG (H+L), at 1:5000 dilution Developed using the odssey technique. Performed under reducing conditions. Predicted band size: 56 kDa Observed band size: 56 kDa |
| Image 2 Alt Text | Human ALK-1/ACVRL1 Western blot (WB) 13103 |
| Image 2 URL | Source image |
Background Information
| Full Name | activin A receptor type II-like 1 |
| Description | Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. On ligand binding, a heteromeric receptor complex forms consisting of two type II and two type I transmembrane serine/threonine kinases. ACVRL1 protein is expressed in certain blood vessels of kidney, spleen, heart and intestine, serving as an important role during vascular development. Mutations in ACVRL1 gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2 and vascular disease. |
| References |
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