| Catalog No. | Size | Price (USD) |
| 14800-RP01-100 | 100 µL | $147.96 |
| 14800-RP01-200 | 200 µL | $251.64 |
| 14800-RP01-400 | 400 µL | $355.32 |
General Information
| Product name | Anti-Alpha SNAP Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human Alpha SNAP |
| Immunogen | Recombinant Human SNAP-alpha Protein (Catalog#14800-H07E) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human SNAP-alpha (rh SNAP-alpha; Catalog#14800-H07E; NP_003818.2; Met1-Arg295). Total IgG was purified by Protein A affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-SNAPA Antibody
Background Information
| Full Name | N-ethylmaleimide-sensitive factor attachment protein, alpha |
| Description | NAPA (NSF Attachment Protein Alpha) is a Protein Coding gene. This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. NAPA represents an anti-apoptotic protein that promotes resistance to cisplatin in cancer cells by inducing the degradation of the tumor suppressor p53. NAPA overexpression decreased the ubiquitination and degradation of synoviolin and reduced p53 protein level. The combination of cisplatin and knockdown of NAPA represents a novel and attractive strategy to eradicate p53-sensitive cancer cells. NAPA-73 as one of the earliest neuronal markers may reflect a difference between the central and peripheral nervous systems. |
