Anti-AP2A2 Antibody, Rabbit Polyclonal sinobiological 207295-T44

$143.00
In stock
SKU
207295-T44
Catalog No.SizePrice (USD)
207295-T44-5050 µL$147.96
207295-T44-100100 µL$251.64
207295-T44-200200 µL$355.32

General Information

Product nameAnti-AP2A2 Antibody, Rabbit Polyclonal
Validated applicationsWB (FAQ Protocol), IHC-P (FAQ Protocol), IP (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman AP2A2
ImmunogenE. coli-derived Human AP2A2 fragment
PreparationProduced in rabbits immunized with E. coli-derived Human AP2A2 fragment, and purified by antigen affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
FormulationPBS, pH7.0 with 0.03% Proclin300
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-ADTAB Antibody; Anti-AP2A2 Antibody; Anti-CLAPA2 Antibody; Anti-DKFZP564D1864 Antibody; Anti-HIP-9 Antibody; Anti-HIP9 Antibody; Anti-HYPJ Antibody; Anti-KIAA0899 Antibody

Image / Experimental Information

Image 1 DescriptionAnti-AP2A2 rabbit polyclonal antibody at 1:500 dilution Lane A: RT-4 Whole Cell Lysate Lane B: U-251 MG Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:104 kDa Observed band size:104 kDa
Image 1 Alt TextHuman AP2A2 Western blot (WB) 31143
Image 1 URLSource image
Image 2 DescriptionAnti-AP2A2 rabbit polyclonal antibody at 1:500 dilution Lane A: RT-4 Whole Cell Lysate Lane B: U-251 MG Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:104 kDa Observed band size:104 kDa
Image 2 Alt TextHuman AP2A2 Immunohistochemistry(IHC) 31144
Image 2 URLSource image
Image 3 DescriptionAnti-AP2A2 rabbit polyclonal antibody at 1:500 dilution Lane A: RT-4 Whole Cell Lysate Lane B: U-251 MG Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:104 kDa Observed band size:104 kDa
Image 3 Alt TextHuman AP2A2 Immunohistochemistry(IHC) 31145
Image 3 URLSource image
Image 4 DescriptionAnti-AP2A2 rabbit polyclonal antibody at 1:500 dilution Lane A: RT-4 Whole Cell Lysate Lane B: U-251 MG Whole Cell Lysate Lysates/proteins at 30 μg per lane. Secondary Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size:104 kDa Observed band size:104 kDa
Image 4 Alt TextHuman AP2A2 Immunoprecipitation(IP) 31146
Image 4 URLSource image

Background Information

DescriptionAP-2 is a stable protein complex comprising 4 domains, which are termed alpha, beta, mu, and sigma. AP2A1 and AP2A2 are homologous human genes that encode the alpha subunit of the AP-2 complex. The AP2A2 transcript is expressed in a broad range of CNS cell lineages. At the tissue level, both AP2A1 and AP2A2 are highly expressed in human cerebellum, but AP2A2 is expressed at lower levels in the cerebral cortex. AP2A2 (Adaptor Related Protein Complex 2 Subunit Alpha 2, also known as HIP9; HYPJ; ADTAB; HIP-9; CLAPA2) is located on human chromosome 11p15.5. The AP2A2 protein is ubiquitously expressed in spleen, brain and other tissues. Structurally, the encoded AP2A2 protein is reported to be 103960 Da in mass.
References
  1. Nelson PT, et al. (2020) The muc6/ap2a2 locus and its relevance to alzheimer's disease: A review. J Neuropathol Exp Neurol 79 (6): 568-584.

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