| Catalog No. | Size | Price (USD) |
| 100356-R034-50 | 50 µL | $177.58 |
| 100356-R034-100 | 100 µL | $340.51 |
General Information
| Product name | Recombinant Anti-Alkaline Phosphatase/ALPL Antibody, Rabbit Monoclonal |
| Validated applications | IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human Alkaline Phosphatase/ALPL |
| Immunogen | A synthetic peptide corresponding to the center region of the Human Alkaline Phosphatase / ALPL |
| Preparation | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the center region of the Human Alkaline Phosphatase / ALPL. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Source | Monoclonal Rabbit IgG Clone #034 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-AP-TNAP Antibody; Anti-APTNAP Antibody; Anti-HOPS Antibody; Anti-HPPA Antibody; Anti-HPPC Antibody; Anti-HPPI Antibody; Anti-HPPO Antibody; Anti-TNALP Antibody; Anti-TNAP Antibody; Anti-TNS-ALP Antibody; Anti-TNSALP Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human ALPL in human adrenal gland with rabbit monoclonal antibody (1:500, formalin-fixed paraffin embedded sections). |
| Image 1 Alt Text | Human Alkaline Phosphatase / ALPL Immunohistochemistry(IHC) 4710 |
| Image 1 URL | Source image |
Background Information
| Full Name | alkaline phosphatase, liver/bone/kidney |
| Description | Alkaline phosphatase (ALPL) is a hydrolase enzyme responsible for removing phosphate groups from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is called dephosphorylation. As the name suggests, alkaline phosphatases are most effective in an alkaline environment. It is sometimes used synonymously as basic phosphatase. Alkaline phosphatases (APs) are ubiquitous in many species, from bacteria to human. Four genes encode AP isoenzymes in humans and rodents. Three AP genes are expressed in a tissue-specific manner (i.e., placental, embryonic, and intestinal AP isoenzymes). Expression of the fourth AP gene is nonspecific to a single tissue and is especially abundant in bone, liver, and kidney. This isoenzyme is also called tissue-nonspecific alkaline phosphatase (TNAP). The enzyme tissue non-specific alkaline phosphatase (TNAP) belongs to the ectophosphatase family. TNAP is present in large amounts in bone in which it plays a role in mineralization. |
| Research Areas |
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| References |
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title: Treatment of cancer utilizing an identified adenosine fingerprint
authors: Amy Elizabeth Anderson; Devika Ashok; ...; Stephen W. Young
date: 2025-05-27
cited_by_count: 0
techniques: Clone Assay; Fluorescence; Formalin-fixed Paraffin-Embedded; Immunostaining; Multiplex Assay; Staining
bioz_score: 93
