Anti-APLP1 Antibody, Rabbit Polyclonal sinobiological 13716-T16

$143.00
In stock
SKU
13716-T16
Catalog No.SizePrice (USD)
13716-T16-5050 µL$147.96
13716-T16-100100 µL$251.64
13716-T16-200200 µL$355.32

General Information

Product nameAnti-APLP1 Antibody, Rabbit Polyclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman APLP1
ImmunogenRecombinant Human APLP1 / Amyloid-like protein 1 protein (Catalog#13716-H08H)
PreparationProduced in rabbits immunized with purified, recombinant Human APLP1 / Amyloid-like protein 1 (rh APLP1 / Amyloid-like protein 1; Catalog#13716-H08H; P51693-1; Met1-Glu580). APLP1 / Amyloid-like protein 1 specific IgG was purified by Human APLP1 / Amyloid-like protein 1 affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-APLP Antibody

Background Information

Full Nameamyloid beta (A4) precursor-like protein 1
DescriptionAPLP1, also known as amyloid-like protein 1, is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. APLP1, together with APLP2, are important modulators of glucose. APLP1 may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described. APLP1 also is a mammalian homologue of amyloid precursor protein (APP). APP is a type I membrane protein that is genetically linked to Alzheimer's disease.
References
  1. Wasco W. et al., 1993, Genomics. 15 (1): 237-9.
  2. Needham BE. et al., 2008, J Pathol. 215 (2): 155-63.
  3. Bayer TA. et al., 2000, Mol Psychiatry. 4 (6): 524-8.
  4. Lee S. et al., 2011, Biochemistry. 50 (24): 5453-64.

title: Liquid biopsy of cerebrospinal fluid identifies neuronal pentraxin receptor (NPTXR) as a biomarker of progression of Alzheimer's disease.
authors: Bryant Lim; Magda Tsolaki; ...; Eleftherios P Diamandis
journal: Clinical chemistry and laboratory medicine
date: 2020-09-17
pmid: 31415236
doi: 10.1515/cclm-2019-0428
cited_by_count: 20
techniques: Concentration Assay; Fluorescence; Incubation; Recombinant
bioz_score: 90

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