| Catalog No. | Size | Price (USD) |
| 107200-T08-50 | 50 µL | $147.96 |
| 107200-T08-100 | 100 µL | $251.64 |
| 107200-T08-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-Aquaporin 9/AQP9 Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human Aquaporin 9/AQP9 |
| Immunogen | A synthetic peptide corresponding to the C-terminus of the Human Aquaporin 9/AQP9 |
| Preparation | Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human Aquaporin 9/AQP9, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-AQP-9 Antibody; Anti-HsT17287 Antibody; Anti-SSC1 Antibody; Anti-T17287 Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human Aquaporin 9 in human liver with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human Aquaporin 9/AQP9 Immunohistochemistry(IHC) 18710 |
| Image 1 URL | Source image |
Background Information
| Full Name | aquaporin 9 |
| Description | Aquaporins (AQPs) are a family of small integral membrane proteins made up of 6 hydrophobic, a-helical, membrane-spanning domains surrounding a highly selective aqueous pore. AQP3, AQP7, and AQP9, termed aqua-glyceroporins, are known to be involved in the transport of water, glycerol, and other small molecules. AQP3 and AQP9 facilitate both transcellular osmotic water flow and glycerol transport as pore-like passive transporters in the keratinocytes of oral epithelia, and may play a key role in not only hydration and the permeability barrier, but also cell proliferation, differentiation, migration, development, and wound healing by generating ATP. Aquaporin-9 (AQP9) is a membrane protein channel that is permeable to a range of small solutes, including glycerol, urea and nucleobases. Aquaporin-9 (AQP9) expression is associated with arsenic sensitivity in leukemia cells. AQP9 might be a novel predictor for the benefit of 5-FU-based chemotherapy in CRC. The identification of AQP9-induced tumor sensitivity to 5-FU highlights the role of AQP9 in regulating chemosensitivity in CRC. aquaporin 9 (AQP9) in the prostate was strictly upregulated by androgen and may represent a novel therapeutic target for several cancers. AQP9 molecular expression mediated by insulin in a concentration-dependent manner in human placenta and provide new evidence that in preeclamptic placentas the mechanisms of insulin signaling may be altered, producing an overexpression of AQP9 that does not correlate with an increase in its functionality. |
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