Anti-ASAM Antibody, Rabbit Polyclonal sinobiological 10794-T16

$128.00
In stock
SKU
10794-T16
Catalog No.SizePrice (USD)
10794-T16-5050 µL$133.15
10794-T16-100100 µL$251.64
10794-T16-200200 µL$340.51

General Information

Product nameAnti-ASAM Antibody, Rabbit Polyclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman ASAM
ImmunogenRecombinant Human ASAM / CLMP protein (Catalog#10794-H08H)
PreparationProduced in rabbits immunized with purified, recombinant Human ASAM / CLMP (rh ASAM / CLMP; Catalog#10794-H08H; NP_079045.1; Met1-Met233). ASAM / CLMP specific IgG was purified by Human ASAM / CLMP affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-ACAM Antibody; Anti-ASAM Antibody; Anti-CSBM Antibody; Anti-CSBS Antibody; Anti-FLJ22415 Antibody; Anti-UNQ318/PRO363 Antibody

Background Information

Full NameCXADR-like membrane protein
DescriptionAdipocyte-specific adhesion molecule (ASAM), also known as ACAM and CLMP, is a type I transmembrane protein and a member of the CTX (cortical thymocyte marker in Xenopus) family within the immunoglobulin superfamily. ASAM protein is highly expressed in the small intestine and placenta, and is found at intermediate levels in the heart, skeletal muscle, colon, spleen, kidney, and lung, and appears in low levels in the liver and peripheral blood leukocytes as well. ASAM is a transmembrane component of tight junctions in epithelial cells that can mediate cell aggregation and regulate transepithelial resistance across polarized epithelial cells. In addition, its expression is strongly correlated with white adipose tissue (WAT) mass of human and rodents with obesity.
References
  1. Eguchi J, et al. (2005) Identification of adipocyte adhesion molecule (ACAM), a novel CTX gene family, implicated in adipocyte maturation and development of obesity. Biochem J. 387(Pt 2): 343-53.
  2. Sze KL, et al. (2008) Expression of CLMP, a novel tight junction protein, is mediated via the interaction of GATA with the Kruppel family proteins, KLF4 and Sp1, in mouse TM4 Sertoli cells. J Cell Physiol. 214(2): 334-44.
  3. Sze KL, et al. (2008) Post-transcriptional regulation of CLMP mRNA is controlled by tristetraprolin in response to TNFalpha via c-Jun N-terminal kinase signalling. Biochem J. 410(3): 575-83.

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