| Catalog No. | Size | Price (USD) |
| 11188-M008-50 | 50 µL | $147.96 |
| 11188-M008-100 | 100 µL | $251.64 |
| 11188-M008-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-B7-H3 Antibody, Mouse Monoclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human B7-H3 |
| Immunogen | Recombinant Human B7-H3/CD276 Protein (Catalog#11188-H08H) |
| Preparation | This product is a recombinant monoclonal antibody expressed from HEK293 cells. |
| Source | Monoclonal Mouse IgG1 Clone #008 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-B7-H3 Antibody; Anti-B7H3 Antibody; Anti-B7RP-2 Antibody; Anti-PSEC0249 Antibody; Anti-UNQ309/PRO352 Antibody
Background Information
| Full Name | CD276 molecule |
| Description | B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an important role in adaptive immune responses, and was shown to either promote or inhibit T-cell responses in various experimental systems. B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is a novel protein structurally related to the B7 family of ligands by the presence of a single set of immunoglobulin-V-like and immunoglobulin-C-like (VC) domains. Previous studies have correlated its overexpression with poor prognosis and decreased tumor-infiltrating lymphocytes in various carcinomas including uterine endometrioid carcinomas, and mounting evidence supports an immuno-inhibitory role in ovarian cancer prognosis. Recently, B7-H3 expression has been reported in several human cancers indicating an additional function of B7-H3 as a regulator of antitumor immunity. |
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| References |
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title: Paper-based enzyme-free immunoassay for rapid detection and subtyping of influenza A H1N1 and H3N2 viruses
authors: Kin Fong Lei; Chia-Hao Huang; ...; Ngan-Ming Tsang
journal: Analytica Chimica Acta
date: 2015-07-01
doi: 10.1016/j.aca.2015.02.071
cited_by_count: 0
techniques: Enzyme-linked Immunosorbent Assay
bioz_score: 90
