Anti-BPIFA2 Antibody, Rabbit Polyclonal sinobiological 13915-T16

$243.00
In stock
SKU
13915-T16
Catalog No.SizePrice (USD)
13915-T16-100100 µL$251.64

General Information

Product nameAnti-BPIFA2 Antibody, Rabbit Polyclonal
Validated applicationsELISA (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman BPIFA2
ImmunogenRecombinant Human BPIFA2 Protein (Catalog#13915-H08H)
PreparationProduced in rabbits immunized with purified, recombinant Human BPIFA2 (rh BPIFA2; Catalog#13915-H08H; Q96DR5; Met1-Ile249). BPIFA2 specific IgG was purified by Human BPIFA2 affinity chromatography.
SourcePolyclonal Rabbit IgG
PurificationProtein A & Antigen Affinity
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-bA49G10.1 Antibody; Anti-C20orf70 Antibody; Anti-PSP Antibody; Anti-SPLUNC2 Antibody; Anti-UNQ510/PRO1025 Antibody

Background Information

Full NameBPI fold containing family A, member 2
DescriptionC20orf70 belongs to the BPI/LBP/Plunc superfamily, Plunc family. PLUNC family is comprised by mucosal secretory proteins that are predicted to be structurally similar to lipid-binding and host-defense proteins including bactericidal/permeability-increasing protein and lipopolysaccharide-binding protein. C20orf70 can be detected in submandibular gland. C20orf70 gene contains 9 distinct gt-ag introns. Transcription produces 6 different mRNAs, 4 alternatively spliced variants and 2 unspliced forms. There are 2 probable alternative promotors, 3 non overlapping alternative last exons and 4 validated alternative polyadenylation sites. The mRNAs appear to differ by truncation of the 3' end. 80 bp of this gene are antisense to spliced gene glopa, raising the possibility of regulated alternate expression. C20orf70 is expected to have molecular function (lipid binding) and to localize in extracellular region. It is a salivary protein of unknown function.
References
  1. Lamesch P, et al. (2007) hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. Genomics. 89(3):307-15.
  2. Vargas PA, et al. (2008) Expression of PLUNC family members in benign and malignant salivary gland tumours. Oral Dis. 14(7):613-9.
  3. Bingle L, et al. (2009) Characterisation and expression of SPLUNC2, the human orthologue of rodent parotid secretory protein. Histochem Cell Biol. 132(3):339-49.

title: Renal progenitor cells revert LPS-induced endothelial-to-mesenchymal transition by secreting CXCL6, SAA4, and BPIFA2 antiseptic peptides.
authors: Fabio Sallustio; Alessandra Stasi; ...; Loreto Gesualdo
journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology
date: 2020-06-01
pmid: 31268775
doi: 10.1096/fj.201900351R
cited_by_count: 28
techniques: Biomarker Discovery; Cytometry; Enzyme-linked Immunosorbent Assay; Expressing; Gene Expression; In Vitro; In Vivo; Incubation; Inhibition; Real-time Polymerase Chain Reaction
bioz_score: 90

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