Recombinant Human MRTO4 / MRT4 protein (Catalog#14639-H07E)
Preparation
Produced in rabbits immunized with purified, recombinant Human MRTO4 / MRT4 (rh MRTO4; Catalog#14639-H07E; Q9UKD2; Met1-Asp239). Total IgG was purified by Protein A affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
MRTO4 (MRT4 Homolog, Ribosome Maturation Factor) is a Protein Coding gene. MRTO4, also known as MRT4, belongs to the universal ribosomal protein uL10 family. This gene encodes a protein sharing a low level of sequence similarity with ribosomal protein P0. MRTO4 is a nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. The precise function of MRTO4 is currently unknown. It appears to be involved in mRNA turnover and ribosome assembly. MRTO4 is widely expressed in the appendix, lymph node, and other tissues. Diseases associated with MRTO4 include Bacterial Conjunctivitis and Robinow Syndrome, Autosomal Dominant 1.
References
Zhao J. et al., 2011, J Proteomics. 75 (2): 588-602.
Havugimana PC. et al., 2012, Cell. 150 (5): 1068-81.
Wu Z. et al., 2012, PLoS One. 7 (8): e43997.
Michalec B. et al., 2010, Int J Biochem Cell Biol. 42 (5): 736-48.