| Catalog No. | Size | Price (USD) |
| 100744-T34-50 | 50 µL | $147.96 |
| 100744-T34-100 | 100 µL | $251.64 |
| 100744-T34-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-CAMKIV Antibody, Rabbit Polyclonal |
| Validated applications | WB (FAQ Protocol), ICC/IF (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CAMKIV |
| Immunogen | A synthetic peptide corresponding to the C-terminus of the Human CAMKIV/CAMK4 |
| Preparation | Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human CAMKIV/CAMK4 , and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-caMK Antibody; Anti-CaMK IV Antibody; Anti-CaMK-GR Antibody; Anti-CaMKIV Antibody
Image / Experimental Information
| Image 1 Description | Immunofluorescence staining of CAMK4 in HeLa cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti-human CAMK4 polyclonal antibody (1:1000) at 4℃ overnight. Then cells were stained with the Alexa Fluor®594-conjugated Goat Anti-rabbit IgG secondary antibody (red)Positive staining was localized to cytoplasm and nucleus. |
| Image 1 Alt Text | Human CaM Kinase 4/CaMKIV Immunofluorescence(IF) 3074 |
| Image 1 URL | Source image |
| Image 2 Description | Immunofluorescence staining of CAMK4 in HeLa cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti-human CAMK4 polyclonal antibody (1:1000) at 4℃ overnight. Then cells were stained with the Alexa Fluor®594-conjugated Goat Anti-rabbit IgG secondary antibody (red)Positive staining was localized to cytoplasm and nucleus. |
| Image 2 Alt Text | Human CaM Kinase 4/CaMKIV Western blot (WB) 6510 |
| Image 2 URL | Source image |
Background Information
| Full Name | calcium/calmodulin-dependent protein kinase IV |
| Description | Ca / calmodulin-dependent protein kinase 4 (CAMKⅣ) belongs to the serine/threonine protein kinase family, and to the Ca /calmodulin-dependent protein kinase subfamily which is widely recognized as an essential enzyme implicated in the phophoinositide amplification cascade. Ca /calmodulin dependent protein kinase (CAMK) can be activated by the introcellular increased Ca and then apt to combine with the target protein. Ca / calmodulin-dependent protein kinase 4 (CAMKⅣ) is a multifunctional CaM-dependent kinase protein with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. All of the isforms of this family, including myosin light chain kinase, phosphorylase kinase, CaMK1, CaMKⅢ and CaMKⅣ have EF-hand structure. |
| Related Pathways |
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| References |
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