| Catalog No. | Size | Price (USD) |
| 10799-RP01-100 | 100 µL | $147.96 |
| 10799-RP01-200 | 200 µL | $251.64 |
| 10799-RP01-400 | 400 µL | $355.32 |
General Information
| Product name | Anti-CXADR/CAR Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CXADR/CAR |
| Immunogen | Recombinant Human CXADR / CAR protein (Catalog#10799-H08H) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human CXADR / CAR (rh CXADR; Catalog#10799-H08H; NP_001329.1; Met1-Gly237). Total IgG was purified by Protein A affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CAR Antibody; Anti-CAR4/6 Antibody; Anti-HCAR Antibody
Background Information
| Full Name | coxsackie virus and adenovirus receptor |
| Description | CXADR (coxsackie virus and adenovirus receptor), also known as CAR, is a type I transmembrane glycoprotein belonging to the CTX family of the Ig superfamily, and is essential for normal cardiac development in the mouse. Proposed as a homophilic cell adhesion molecule, CXADR is a component of the epithelial apical junction complex that is essential for the tight junction integrity, and probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN). Mature mouse CXADR structrually comprises a 218 aa extracellular domain (ECD) with a V-type (D1) and a C2-type (D2) Ig-like domain, a 21 aa transmembrane segment and a 17 aa intracellular domain, among which,D1 is thought to be responsible for homodimer formation in trans within tight junctions. The ECD of mouse CXADR shares 97%, 9% sequence identity with the corresponding regions of rat, human CXADR. |
| References |
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