| Catalog No. | Size | Price (USD) |
| 100547-T08-50 | 50 µL | $147.96 |
| 100547-T08-100 | 100 µL | $251.64 |
| 100547-T08-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-Caveolin-3/CAV3 Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human, Mouse, Rat |
| Specificity | Human, Mouse, Rat |
| Immunogen | A synthetic peptide corresponding to the N-terminus of the Human CAV3 |
| Preparation | Produced in rabbits immunized with A synthetic peptide corresponding to the N-terminus of the Human CAV3, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-LGMD1C Antibody; Anti-LQT9 Antibody; Anti-MPDT Antibody; Anti-RMD2 Antibody; Anti-VIP-21 Antibody; Anti-VIP21 Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining CAV3 in human skeletal muscle with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections). |
| Image 1 Alt Text | Mouse CAV3 Immunohistochemistry(IHC) 4594 |
| Image 1 URL | Source image |
| Image 2 Description | Immunochemical staining CAV3 in human skeletal muscle with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections). |
| Image 2 Alt Text | Mouse CAV3 Immunohistochemistry(IHC) 4595 |
| Image 2 URL | Source image |
| Image 3 Description | Immunochemical staining CAV3 in human skeletal muscle with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections). |
| Image 3 Alt Text | Mouse CAV3 Immunohistochemistry(IHC) 17974 |
| Image 3 URL | Source image |
| Image 4 Description | Immunochemical staining CAV3 in human skeletal muscle with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections). |
| Image 4 Alt Text | Mouse CAV3 Immunohistochemistry(IHC) 17984 |
| Image 4 URL | Source image |
| Image 5 Description | Immunochemical staining CAV3 in human skeletal muscle with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections). |
| Image 5 Alt Text | Mouse CAV3 Immunohistochemistry(IHC) 17990 |
| Image 5 URL | Source image |
Background Information
| Full Name | caveolin 3 |
| Description | Caveolinopathies are a heterogeneous family of genetic pathologies arising from alterations of the caveolin-3 gene (CAV3), encoding for the isoform specifically constituting muscle caveolae. Caveolin-3 (CAV3) is a principal structural protein of the caveolae membrane domains, which has been reported to participate in cell signaling as well as the maintenance of cell structure. Mutations in the CAV3 gene encoding caveolin-3 (Cav3), a scaffolding protein integral to caveolae in cardiomyocytes, have been associated with the congenital long-QT syndrome (LQT9). Mutations in caveolin-3 (CAV3) can lead to different clinical phenotypes affecting skeletal or cardiac muscles. Mutations in CAV3 lead to various neuromuscular phenotypes with partial overlap, including limb-girdle muscular dystrophy type 1C (LGMD1C), rippling muscle disease, distal myopathy, and isolated hyperCKemia. |
| References |
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