| Catalog No. | Size | Price (USD) |
| 203552-T02-50 | 50 µL | $147.96 |
| 203552-T02-100 | 100 µL | $251.64 |
| 203552-T02-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-ARL2BP Antibody, Rabbit Polyclonal |
| Validated applications | ICC/IF (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human ARL2BP |
| Immunogen | E. coli-derived Human ARL2BP fragment |
| Preparation | Produced in rabbits immunized with E. coli-derived Human ARL2BP fragment, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | PBS, pH7.0 with 0.03% Proclin300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-BART Antibody; Anti-BART1 Antibody; Anti-RP66 Antibody
Image / Experimental Information
| Image 1 Description | Immunofluorescence staining of ARL2BP in U2OS cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti-Human ARL2BP polyclonal antibody (dilution ratio 1:200) at 4℃ overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Nucleus and Cytoplasm. |
| Image 1 Alt Text | Human ARL2BP Immunofluorescence(IF) 24342 |
| Image 1 URL | Source image |
Background Information
| Full Name | ADP-ribosylation factor-like 2 binding protein |
| Description | ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. ARL2BP binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of ARL2BP or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. ARL2BP is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity. ARL2BP, together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. ARL2BP may play a role as an effector of ARL2. |
| References |
|
-HD12AU0778-200-U2OS-IF.png){kind=link}