| Catalog No. | Size | Price (USD) |
| 11007-R001-C-25 | 25 Tests | $133.30 |
| 11007-R001-C-100 | 100 Tests | $414.71 |
General Information
| Product name | Recombinant Anti-CD20 Antibody (PerCP), Rabbit Monoclonal |
| Validated applications | FCM (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CD20 |
| Immunogen | Human CD20 Transfected CHO Cells |
| Preparation | This antibody was obtained from a rabbit immunized with purified, Human CD20 Transfected CHO Cells and conjugated with PerCP under optimum conditions, the unreacted PerCP was removed. |
| Source | Monoclonal Rabbit IgG Clone #001 |
| Purification | Protein A |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Concentration | 5 μl/Test, 0.1 mg/ml |
| Conjugate | PerCP |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
Synonyms: Anti-B1 Antibody; Anti-Bp35 Antibody; Anti-CD20 Antibody; Anti-CVID5 Antibody; Anti-FMC7 Antibody; Anti-LEU-16 Antibody; Anti-S7 Antibody
Image / Experimental Information
| Image 1 Description | Profile of anti-CD20 reactivity on peripheral blood lymphocytes analyzed by flow cytometry. |
| Image 1 Alt Text | Human CD20/MS4A1 Flow Cytometry (FC) 2624 |
| Image 1 URL | Source image |
Background Information
| Full Name | membrane-spanning 4-domains, subfamily A, member 1 |
| Description | CD20 (membrane-spanning 4-domains, subfamily A, member 1), also known as MS4A1, is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. CD20 / MS4A1 is expressed in all stages of B cell development except the first and last. CD20 / MS4A1 is present from pre-pre B cells through memory cells, but not on either pro-B cells or plasma cells. It is a B-lymphocyte surface molecule that plays a role in the development and differentiation of B-cells into plasma cells. CD20 / MS4A1may be involved in the regulation of B-cell activation and proliferation. Defects in CD20 / MS4A1 are the cause of immunodeficiency common variable type 5(CVID5). CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections, and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells are usually in the normal range but can be very low. |
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