| Catalog No. | Size | Price (USD) |
| 10427-R005-1 | 1 mL | $1,969.87 |
| 10427-R005-20 | 20 µL | $118.49 |
| 10427-R005-50 | 50 µL | $177.58 |
| 10427-R005-100 | 100 µL | $340.51 |
General Information
| Product name | Recombinant Anti-CD204/MSR1 Antibody, Rabbit Monoclonal |
| Validated applications | ELISA (FAQ Protocol), ELISA(Det) (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CD204/MSR1 |
| Immunogen | Recombinant Human MSR1 protein (Catalog#10427-H07H) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human MSR1 (rh MSR1; Catalog#10427-H07H; NP_619729.1; Lys 77-Leu 451). |
| Source | Monoclonal Rabbit IgG Clone #005 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CD204 Antibody; Anti-phSR1 Antibody; Anti-phSR2 Antibody; Anti-SCARA1 Antibody; Anti-SR-A Antibody; Anti-SR-AI Antibody; Anti-SR-AII Antibody; Anti-SR-AIII Antibody; Anti-SRA Antibody
Background Information
| Full Name | macrophage scavenger receptor 1 |
| Description | Macrophage scavenger receptor types I and II, also known as Macrophage acetylated LDL receptor I and II, Scavenger receptor class A member 1, CD24, MSR1, and SCARA1, is a single-pass type II membrane protein that contains one collagen-like domain and one SRCR domain. Macrophages are distributed in all peripheral tissues and play a critical role in the first line of the innate immune defenses against bacterial infection by phagocytosis of bacterial pathogens through the macrophage scavenger receptor 1 (MSR1). MSR1 / SCARA1 is one of the membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low-density lipoproteins (LDL). MSR1 / SCARA1 is also involved in chronic inflammation which is a risk factor for prostate cancer. MSR1 1 gene was identified as a candidate susceptibility gene for hereditary prostate cancer and as a risk factor for sporadic prostate cancer. |
| References |
|
title: Hemosiderin-Laden Macrophages in Canine Mammary Carcinomas
authors: Giada Giambrone; Cecilia Vullo; ...; Cinzia Benazzi
journal: Animals : An Open Access Journal From Mdpi
date: 2023-11-24
doi: 10.3390/ani13233634
pmcid: 10705201
cited_by_count: 0
techniques: Marker; Staining
bioz_score: 91
