| Catalog No. | Size | Price (USD) |
| 10039-T24-50 | 50 µL | $147.96 |
| 10039-T24-100 | 100 µL | $251.64 |
| 10039-T24-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-CD27/TNFRSF7 Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol), IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CD27/TNFRSF7 |
| Immunogen | Recombinant Human CD27 protein (Catalog#10039-H31H) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human CD27 (rh CD27; Catalog#10039-H31H; P26842; Met1-Ile192). CD27 specific IgG was purified by Human CD27 affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-S152 Antibody; Anti-S152. LPFS2 Antibody; Anti-T14 Antibody; Anti-TNFRSF7 Antibody; Anti-Tp55 Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human CD27 in human spleen with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections). |
| Image 1 Alt Text | Human CD27/TNFRSF7 Immunohistochemistry(IHC) 7739 |
| Image 1 URL | Source image |
| Image 2 Description | Immunochemical staining of human CD27 in human spleen with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections). |
| Image 2 Alt Text | Human CD27/TNFRSF7 Immunohistochemistry(IHC) 7740 |
| Image 2 URL | Source image |
Background Information
| Full Name | CD27 molecule |
| Description | CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a type I transmembrane glycoprotein of about 55 kDa existing as disulfide-linked homodimer, CD27 has been shown to play roles in lymphoid proliferation, differentiation, and apoptosis.It has an important role in the generation of T cell immunity and is an robust marker for normal memory B cells. It is a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD70 on lymphocytes and dendritic cells. The CD27-CD70 interaction is required for Th1 generation responses to differentiation signals and long-term maintenance of T cell immunity, and meanwhile, plays a key role in regulating B-cell differentiation, activation and immunoglobulin synthesis. |
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