| Catalog No. | Size | Price (USD) |
| 11524-R007-F-25 | 25 Tests | $44.43 |
| 11524-R007-F-100 | 100 Tests | $103.68 |
General Information
| Product name | Recombinant Anti-CD28 Antibody (FITC), Rabbit Monoclonal |
| Validated applications | FCM (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CD28 |
| Immunogen | Recombinant Human CD28 Protein (Catalog#11524-H08H) |
| Preparation | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD28 (rh CD28; Catalog#11524-H08H; P10747-1; Met1-Pro152) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| Source | Monoclonal Rabbit IgG Clone #007 |
| Purification | Protein A |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Concentration | 5 μl/Test, 0.1 mg/ml |
| Conjugate | FITC |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! |
Synonyms: Anti-Tp44 Antibody
Image / Experimental Information
| Image 1 Description | Flow cytometric analysis of Human CD28 expression on human whole blood lymphocytes. Cells were stained with FITC-conjugated anti-Human CD28. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| Image 1 Alt Text | Human CD28/TP44 Flow Cytometry (FC) 5276 |
| Image 1 URL | Source image |
Background Information
| Full Name | CD28 molecule |
| Description | CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell response pathways. B7/CD28 family members, which can augment or antagonize T-cell receptor signaling, in the regulation of central and peripheral T-cell tolerance. CD28 is thus involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. |
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