Anti-CD38 Antibody, Mouse Monoclonal sinobiological 10818-MM12T

$143.00
In stock
SKU
10818-MM12T
Catalog No.SizePrice (USD)
10818-MM12T-5050 µL$147.96
10818-MM12T-100100 µL$251.64
10818-MM12T-200200 µL$355.32

General Information

Product nameAnti-CD38 Antibody, Mouse Monoclonal
Validated applicationsFCM (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman CD38
ImmunogenRecombinant Human CD38/ADPRC1 Protein (Catalog#10818-H08H)
PreparationThis product is a recombinant monoclonal antibody expressed from HEK293 cells.
SourceMonoclonal Mouse IgG1 Clone #12
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-ADPRC 1 Antibody; Anti-ADPRC1 Antibody; Anti-cADPR1 Antibody

Image / Experimental Information

Image 1 DescriptionFlow cytometric analysis of Human CD38 expression on human whole blood lymphocytes. Cells were stained with purified anti-Human CD38, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
Image 1 Alt TextHuman CD38/ADPRC1 Flow Cytometry (FC) 17538
Image 1 URLSource image

Background Information

Full NameCD38 molecule
DescriptionThe cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 38 (CD38), also known as ADP-ribosyl cyclase, is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4 , CD8 , B and natural killer cells. It shares several characteristics with ADP-ribosyl cyclase 2 CD157. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD to ADP-ribose. It also functions in cell adhesion, signal transduction and calcium signaling. CD38 has been used as a prognostic marker in leukemia. It can also be used to identify plasma cells.
Research Areas
  • Cancer Drug Targets
References
  1. Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  2. Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  3. Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.

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