| Catalog No. | Size | Price (USD) |
| 10239-MM04-50 | 50 µL | $147.96 |
| 10239-MM04-100 | 100 µL | $251.64 |
| 10239-MM04-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-CD40 Ligand/TNFSF5 Antibody, Mouse Monoclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CD40 Ligand/TNFSF5 No cross-reactivity in ELISA with Human TNFRSF8 Human CD40 Mouse CD27 E.coli cell lysate |
| Immunogen | Recombinant Human CD40L / CD154 / TNFSF5 protein (Catalog#10239-H08E) |
| Preparation | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD40L / CD154 / TNFSF5 (rh CD40L / CD154 / TNFSF5; Catalog#10239-H08E; NP_000065.1; Glu 108-Leu 261). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Source | Monoclonal Mouse IgG1 Clone #04 |
| Purification | Protein A |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CD154 Antibody; Anti-CD40-L Antibody; Anti-CD40L Antibody; Anti-gp39 Antibody; Anti-hCD40L Antibody; Anti-HIGM1 Antibody; Anti-IGM Antibody; Anti-IMD3 Antibody; Anti-T-BAM Antibody; Anti-TNFSF5 Antibody; Anti-TRAP Antibody
Background Information
| Full Name | CD40 ligand |
| Description | The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD154, also known as CD40 ligand or CD40L, is a member of the TNF superfamily. While CD154 was originally found on T cell surface, its expression has since been found on a wide variety of cells, including platelets, mast cells, macrophages and NK cells. CD154's ability is achieved through binding to the CD40 on antigen-presenting cells (APC). In the macrophage cells, the primary signal for activation is IFN-γ from Th1 type CD4 T cells. The secondary signal is CD40L on the T cell, which interacting with the CD40 molecules, helping increase the level of activation. |
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