Anti-CD63 Antibody (FITC), Mouse Monoclonal sinobiological 11271-MM03-F

$100.00
In stock
SKU
11271-MM03-F
Catalog No.SizePrice (USD)
11271-MM03-F-2525 Tests$103.68
11271-MM03-F-100100 Tests$325.84

General Information

Product nameAnti-CD63 Antibody (FITC), Mouse Monoclonal
Validated applicationsFCM (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman CD63
ImmunogenRecombinant Human CD63 protein (Catalog#11271-H08H)
PreparationThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD63 (rh CD63; Catalog#11271-H08H; P08962-1; Ala 103-Val 203) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
SourceMonoclonal Mouse IgG1 Clone #03
PurificationProtein A
FormulationPBS solution containing 0.5% BSA and 0.03%ProClin300
Concentration10 μl/Test, 0.1 mg/ml
ConjugateFITC
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze !

Synonyms: Anti-AD1 Antibody; Anti-HOP-26 Antibody; Anti-ME491 Antibody; Anti-MLA1 Antibody; Anti-OMA81H Antibody; Anti-Pltgp40 Antibody; Anti-TSPAN30 Antibody

Image / Experimental Information

Image 1 DescriptionProfile of anti-CD63 reactivity on MCF-7 cells analyzed by flow cytometry.
Image 1 Alt TextHuman CD63 Flow Cytometry (FC) 2612
Image 1 URLSource image

Background Information

Full NameCD63 molecule
DescriptionThe cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 63 (CD63) is a member of the CD family and the transmembrane 4 superfamily, also known as the tetraspanin family. CD63 is a cell surface glycoprotein characterized by the presence of four hydrophobic domains. CD63 had functions in mediating signal transduction processes and then regulate a variety of cellular processes such as cell proliferation, activation and motility. It has been reported that CD63 protein associated with tumor progression and served as a blood platelet activation marker and the deficiency of this protein may be associated with Hermansky-Pudlak syndrome.
References
  1. Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  2. Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  3. Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
  4. Radford KJ, et al. (1996) Associates with Transmembrane 4 Superfamily Members, CD9 and CD81, and with beta 1 Integrins in Human Melanoma. Biochemical Biophysical Research Communications. 222(1): 13-18.
  5. Metzelaar MJ, et al. (1991) CD63 antigen, A novel lysosomal membrane glycoprotein, cloned by a screening procedure for intracellular antigens in eukaryotic cells. The journal of biological chemistry. 266: 3239-45.

title: A Kind of IgE-Independent Chronic Urticarial Mediated by MRGPRX2
authors: Delu Che; Tao Zhang; ...; Langchong He
journal: SSRN Electronic Journal
date: 2019-01-01
doi: 10.2139/ssrn.3381129
cited_by_count: 0
techniques: Isolation; Purification
bioz_score: 90

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