Anti-CD81 Antibody (APC), Mouse Monoclonal sinobiological 14244-MM03-A

$129.00
In stock
SKU
14244-MM03-A
Catalog No.SizePrice (USD)
14244-MM03-A-2525 Tests$133.30
14244-MM03-A-100100 Tests$414.71

General Information

Product nameAnti-CD81 Antibody (APC), Mouse Monoclonal
Validated applicationsFCM (FAQ Protocol)
Species reactivityReacts with: Human
SpecificityHuman CD81
ImmunogenRecombinant Human CD81/TAPA1 Protein (Catalog#14244-HNCH)
PreparationThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD81/TAPA1 (rh CD81/TAPA1; Catalog#14244-HNCH; NP_004347.1; Phe113-Lys201) and conjugated with APC under optimum conditions, the unreacted APC was removed.
SourceMonoclonal Mouse IgG2b Clone #03
PurificationProtein A
FormulationPBS solution containing 0.5% BSA and 0.09% sodium azide
Concentration5 μl/Test, 0.1 mg/ml
ConjugateAPC
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for twelve months without detectable loss of activity. Protected from prolonged exposure to light. Do not freeze ! Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.

Synonyms: Anti-CVID6 Antibody; Anti-S5.7 Antibody; Anti-TAPA-1 Antibody; Anti-TAPA1 Antibody; Anti-TSPAN28 Antibody

Image / Experimental Information

Image 1 DescriptionFlow cytometric analysis of Human CD81 expression on human whole blood lymphocytes. Cells were stained with APC-conjugated anti-Human CD81. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
Image 1 Alt TextHuman CD81/TAPA1 Flow Cytometry (FC) 17163
Image 1 URLSource image

Background Information

Full NameCD81 molecule
DescriptionCD81, also known as TAPA-1, belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Members of this family mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.CD81 is a widely expressed cell-surface protein involved in an astonishing variety of biologic responses. It is related to adhesion, morphology, activation, proliferation, and differentiation of B, T, and other cells. On B cells CD81 is part of a complex with CD21, CD19, and Leu13. This complex reduces the threshold for B cell activation via the B cell receptor by bridging Ag specific recognition and CD21-mediated complement recognition.
References
  1. Petracca R. et al., 2000, J Virol. 74 (10): 4824-30.
  2. Bartosch B. et al., 2003, The Journal of Biological Chemistry. 278 (43): 41624-30.
  3. Clark KL. et al., 2001, Journal of Immunology. 167 (9): 5115-21.

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