| Catalog No. | Size | Price (USD) |
| 107030-T08-50 | 50 µL | $147.96 |
| 107030-T08-100 | 100 µL | $251.64 |
| 107030-T08-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-Claudin 10 Antibody, Rabbit Polyclonal |
| Validated applications | IHC-P (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human Pongo abelii (Species predicted to react based on 100% sequence homology) |
| Immunogen | A synthetic peptide corresponding to the center region of the Human Claudin 10 |
| Preparation | Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human Claudin 10, and purified by antigen affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-CPETRL3 Antibody; Anti-HELIX Antibody; Anti-OSP-L Antibody; Anti-OSPL Antibody
Image / Experimental Information
| Image 1 Description | Immunochemical staining of human CLDN10 in human pancreas with rabbit polyclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. |
| Image 1 Alt Text | Human Claudin 10 Immunohistochemistry(IHC) 19104 |
| Image 1 URL | Source image |
Background Information
| Full Name | claudin 10 |
| Description | Mice lacking distal tubular expression of CLDN10, the gene encoding the tight junction protein Claudin-10, show enhanced paracellular magnesium and calcium permeability and reduced sodium permeability in the thick ascending limb (TAL), leading to a urine concentrating defect. CLDN1 and CLDN10 may play important roles in the development of AIS to LPA. Overexpression of CLDN1 and CLDN10 indicates a favorable prognosis for overall survival in some patients with lung adenocarcinoma. Expression of CLDN10 may be regulated by the c-fos pathway. |
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