| Catalog No. | Size | Price (USD) |
| 12712-T16-50 | 50 µL | $147.96 |
| 12712-T16-100 | 100 µL | $251.64 |
| 12712-T16-200 | 200 µL | $355.32 |
General Information
| Product name | Anti-CREB3L1 Antibody, Rabbit Polyclonal |
| Validated applications | ELISA (FAQ Protocol) |
| Species reactivity | Reacts with: Human |
| Specificity | Human CREB3L1 |
| Immunogen | Recombinant Human CREB3L1 / OASIS protein (Catalog#12712-H08H) |
| Preparation | Produced in rabbits immunized with purified, recombinant Human CREB3L1 / OASIS (rh CREB3L1 / OASIS; Catalog#12712-H08H; Q96BA8-1; Glu396- Ser519). CREB3L1 / OASIS specific IgG was purified by Human CREB3L1 / OASIS affinity chromatography. |
| Source | Polyclonal Rabbit IgG |
| Purification | Protein A & Antigen Affinity |
| Formulation | 0.2 μm filtered solution in PBS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Shipping | This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
| Storage | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles. |
Synonyms: Anti-C16DELp11.2 Antibody; Anti-DEL16p11.2 Antibody; Anti-OASIS Antibody; Anti-OI16 Antibody; Anti-PSEC0238 Antibody
Background Information
| Full Name | cAMP responsive element binding protein 3-like 1 |
| Description | CREB3L1, also known as OASIS, is a cellular transcription factor synthesized as a membrane-bound precursor. It is a putative endoplasmic reticulum (ER) stress sensor in astrocytes with a mechanism of activation. OASIS mRNA expression was detected in pancreatic β-cell lines and rodent islets, and the expression level was up-regulated by ER stress-inducing compounds. CREB3L1 may have a role in pancreas development. CREB3L1 may also play an important role in limiting virus spread by inhibiting proliferation of virus-infected cells. In vitro, CREB3L1 binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE. It may play a role in gliosis. |
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