Anti-CD20 Antibody, Mouse Monoclonal sinobiological 11007-MM06

$143.00
In stock
SKU
11007-MM06
Catalog No.SizePrice (USD)
11007-MM06-5050 µL$147.96
11007-MM06-100100 µL$251.64
11007-MM06-200200 µL$355.32

General Information

Product nameAnti-CD20 Antibody, Mouse Monoclonal
Validated applicationsIHC-P (FAQ Protocol)
Species reactivityReacts with: Human, Cynomolgus
SpecificityHuman, Cynomolgus
ImmunogenRecombinant Human CD20/MS4A1 Protein (Catalog#11007-H07H2)
PreparationThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD20/MS4A1 (rh CD20/MS4A1; Catalog#11007-H07H2; NP_068769.2; Glu213-Pro297). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
SourceMonoclonal Mouse IgG1 Clone #06
PurificationProtein A
Formulation0.2 μm filtered solution in PBS
ConjugateUnconjugated
FormLiquid
ShippingThis antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
StorageThis antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Synonyms: Anti-B1 Antibody; Anti-Bp35 Antibody; Anti-CD20 Antibody; Anti-CVID5 Antibody; Anti-FMC7 Antibody; Anti-LEU-16 Antibody; Anti-S7 Antibody

Image / Experimental Information

Image 1 DescriptionImmunochemical staining CD20 in human tonsil with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections.
Image 1 Alt TextHuman CD20 Immunohistochemistry(IHC) 20313
Image 1 URLSource image
Image 2 DescriptionImmunochemical staining CD20 in human tonsil with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections.
Image 2 Alt TextHuman CD20 Immunohistochemistry(IHC) 20314
Image 2 URLSource image
Image 3 DescriptionImmunochemical staining CD20 in human tonsil with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections.
Image 3 Alt TextHuman CD20 Immunohistochemistry(IHC) 21219
Image 3 URLSource image
Image 4 DescriptionImmunochemical staining CD20 in human tonsil with mouse monoclonal antibody at 1:60 dilution, formalin-fixed paraffin embedded sections.
Image 4 Alt TextHuman CD20 Immunohistochemistry(IHC) 21240
Image 4 URLSource image

Background Information

Full Namemembrane-spanning 4-domains, subfamily A, member 1
DescriptionCD20 (membrane-spanning 4-domains, subfamily A, member 1), also known as MS4A1, is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. CD20 / MS4A1 is expressed in all stages of B cell development except the first and last. CD20 / MS4A1 is present from pre-pre B cells through memory cells, but not on either pro-B cells or plasma cells. It is a B-lymphocyte surface molecule that plays a role in the development and differentiation of B-cells into plasma cells. CD20 / MS4A1may be involved in the regulation of B-cell activation and proliferation. Defects in CD20 / MS4A1 are the cause of immunodeficiency common variable type 5(CVID5). CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections, and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells are usually in the normal range but can be very low.
Research Areas
  • Cancer Drug Targets
Tags
  • Cancer Immunotherapy
  • Immune Checkpoint
  • Immunotherapy
  • Targeted Therapy
References
  1. Tedder TF, et al. (1988) Isolation and structure of a cDNA encoding the B1 (CD20) cell-surface antigen of human B lymphocytes. Proc Natl Acad Sci. 85(1): 208-12.
  2. Cragg MS, et al. (2005) The biology of CD20 and its potential as a target for mAb therapy. Curr Dir Autoimmun. 8: 140-74..
  3. Polyak MJ, et al. (2003) A cholesterol-dependent CD20 epitope detected by the FMC7 antibody. Leukemia. 17(7): 1384-9.

title: Machine learning–based integrative analysis identifies CXCL13-driven tertiary lymphoid structures as favorable immune and prognostic features in osteosarcoma
authors: Jie Jiang; Jiuhui Xu; ...; Xiaodong Tang
journal: Cellular Oncology
date: 2026-05-16
pmid: 42143177
doi: 10.1007/s13402-026-01226-1
cited_by_count: 0
techniques: Immunofluorescence; Immunohistochemistry; Incubation; Microscopy; Multiplex Assay; Software
bioz_score: 94

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