Recombinant Human DCBLD2 / ESDN / CLCP1 Protein (Catalog#13615-H08H)
Preparation
Produced in rabbits immunized with purified, recombinant Human DCBLD2 / ESDN / CLCP1 (rh DCBLD2 / ESDN / CLCP1; Catalog#13615-H08H; NP_563615.3; Met1-Ala482). DCBLD2 / ESDN / CLCP1 specific IgG was purified by Human DCBLD2 / ESDN / CLCP1 affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A & Antigen Affinity
Formulation
0.2 μm filtered solution in PBS
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Synonyms: Anti-CLCP1 Antibody; Anti-ESDN Antibody
Background Information
Full Name
discoidin, CUB and LCCL domain containing 2
Description
DCBLD2, also known as ESDN and CLCP1, localizes in various compartments. DCBLD2 is up-regulated in lung cancers and is regulated by transcription factor AP-2 alpha (TFAP2A), a component of activator protein-2 (AP-2) that is known to regulate IL-8 production in human lung fibroblasts and epithelial cells. DCBLD2 could be related to FEV(1)-related phenotypes in asthmatics. DCBLD2 gene is expressed at very high level. DCBLD2 is proposed to participate in processes such as intracellular receptor mediated signaling pathway, negative regulation of cell growth and so on.
References
Kobuke K. et al., 2001, J Biol Chem. 276 (36): 34105-14.
Adeghi MM. et al., 2007, Am J Transplant. 7 (9): 2098-105.
Chen Y. et al., 2007, Proteomics. 7 (14): 2384-97.
Park TJ. et al., 2012, J Korean Med Sci. 27 (4): 343-9.